HitPredict

Interactor 1: ANK2 (Q01484)
Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin)
Gene: ANK2

Interactor 2: EHD4 (Q9H223)
EH domain-containing protein 4 (Hepatocellular carcinoma-associated protein 10/11) (PAST homolog 4)
Gene: EHD4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20489164
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005769 - early endosome GO:0005886 - plasma membrane GO:0006897 - endocytosis GO:0072659 - protein localization to plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 3957 Hs			1 541
+	Hs
		965155 ANK2_HUMAN (1-3957): 0: 1910: 100.00		EHD1_HUMAN (1-535): 0: 823: 74.95
+	Hs
		965166 ANK2_HUMAN (1-3957): 0: 1910: 100.00		EHD3_HUMAN (1-538): 0: 805: 74.72
+	Hs
		965167 ANK2_HUMAN (1-3957): 0: 1910: 100.00		EHD2_HUMAN (1-535): 0: 799: 68.89
+	Mm
		1208055 ANK2_MOUSE (1-3957): 0: 1769: 80.90		EHD4_MOUSE (1-541): 0: 843: 97.04
+	Mm
		1208059 ANK2_MOUSE (1-3957): 0: 1769: 80.90		EHD1_MOUSE (1-535): 0: 822: 74.77
+	Mm
		1208057 ANK2_MOUSE (1-3957): 0: 1769: 80.90		EHD3_MOUSE (1-538): 0: 799: 75.09
+	Mm
		1206516 ANK2_MOUSE (1-3957): 0: 1769: 80.90		EHD2_MOUSE (1-541): 0: 796: 67.77
+	Hs
		787897 ANK2_HUMAN (1-3957): 0: 1910: 100.00		EPS15_HUMAN (449-532): 1.75e-12: 72.3: 35.29
+	Hs
		1331788 ANFY1_HUMAN (2-203): 1.72e-30: 135: 16.74		EHD1_HUMAN (1-535): 0: 823: 74.95
+	Hs
		1349321 ANFY1_HUMAN (2-203): 1.72e-30: 135: 16.74		EHD3_HUMAN (1-538): 0: 805: 74.72
+	Hs
		1021469 ANK3_HUMAN (3120-3957): 1.41e-10: 70.3: 8.79		EP15R_HUMAN (444-533): 2.57e-09: 61.9: 27.47