HitPredict

Interactor 1: FAK1 (Q05397)
Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)
Gene: PTK2

Interactor 2: CCD18 (Q5T9S5)
Coiled-coil domain-containing protein 18 (Sarcoma antigen NY-SAR-24)
Gene: CCDC18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1052 Hs			1 1454
+	Hs
		1051000 FAK1_HUMAN (1-1052): 0: 1141: 100.00		NUMA1_HUMAN (2-478): 8.79e-15: 82.6: 11.39
+	Hs
		400859 RAF1_HUMAN (106-714): 5.35e-121: 387: 16.90		EEA1_HUMAN (1-997): 1.83e-39: 163: 12.92
+	Hs
		557552 SRC_HUMAN (415-689): 1.15e-113: 363: 38.77		MYH4_HUMAN (391-1453): 3.17e-45: 181: 12.92
+	Hs
		400389 RAF1_HUMAN (106-714): 5.35e-121: 387: 16.90		MYH10_HUMAN (942-1454): 6.03e-23: 109: 12.28
+	Hs
		156825 RAF1_HUMAN (106-714): 5.35e-121: 387: 16.90		CTRO_HUMAN (30-786): 3.04e-21: 103: 14.12
+	Hs
		400392 RAF1_HUMAN (106-714): 5.35e-121: 387: 16.90		MYH11_HUMAN (2-511): 5.25e-20: 99.5: 12.31
+	Hs
		456090 FES_HUMAN (85-681): 3.06e-129: 414: 22.73		DESP_HUMAN (289-1164): 1.11e-10: 68.9: 19.50
+	Hs
		401684 RAF1_HUMAN (106-714): 5.35e-121: 387: 16.90		MYH13_HUMAN (1-485): 1.59e-18: 94.5: 9.69
+	Hs
		400850 RAF1_HUMAN (106-714): 5.35e-121: 387: 16.90		NUMA1_HUMAN (2-478): 8.79e-15: 82.6: 11.39
+	Hs
		400388 RAF1_HUMAN (106-714): 5.35e-121: 387: 16.90		MYH9_HUMAN (2-349): 8.86e-12: 72.6: 8.33
+	Mm
		1000208 RAF1_MOUSE (106-714): 6.13e-120: 384: 16.75		ROCK2_MOUSE (611-1307): 5.24e-12: 73.2: 20.46
+	Hs
		400234 RAF1_HUMAN (106-714): 5.35e-121: 387: 16.90		DESP_HUMAN (289-1164): 1.11e-10: 68.9: 19.50
+	Hs
		710246 EPHA2_HUMAN (373-774): 5.28e-116: 383: 31.46		GOGB1_HUMAN (1-438): 2.85e-09: 64.5: 10.38
+	Hs
		440658 FYN_HUMAN (415-689): 1.13e-112: 361: 37.32		MY18A_HUMAN (524-1183): 2.16e-13: 77.8: 20.43
+	Hs
		440414 FYN_HUMAN (415-689): 1.13e-112: 361: 37.32		MYH9_HUMAN (2-349): 8.86e-12: 72.6: 8.33
+	Hs
		117127 J3QRU1_HUMAN (415-689): 8.71e-112: 359: 37.68		MYH9_HUMAN (2-349): 8.86e-12: 72.6: 8.33
+	Hs
		463006 YES_HUMAN (415-689): 7.5e-112: 359: 37.68		MYH9_HUMAN (2-349): 8.86e-12: 72.6: 8.33
+	Hs
		440337 FYN_HUMAN (415-689): 1.13e-112: 361: 37.32		DESP_HUMAN (289-1164): 1.11e-10: 68.9: 19.50
+	Hs
		439934 LCK_HUMAN (412-691): 6.94e-111: 355: 37.37		DESP_HUMAN (289-1164): 1.11e-10: 68.9: 19.50
+	Hs
		440078 LCK_HUMAN (412-691): 6.94e-111: 355: 37.37		GOGB1_HUMAN (1-438): 2.85e-09: 64.5: 10.38