HitPredict

Interactor 1: IF4A2 (Q14240)
Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2)
Gene: EIF4A2

Interactor 2: IBTK (Q9P2D0)
Inhibitor of Bruton tyrosine kinase (IBtk)
Gene: IBTK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.80	0.675

Property	Details
Experiments	29395067, 17353931
Identification Methods	proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~DEAD
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 407 Hs			1 1353
+	Hs
		892922 IF4A1_HUMAN (3-407): 2.35e-159: 456: 89.88		IBTK_HUMAN (1-1353): 0: 1106: 100.00
+	Hs
		134233 DDX3X_HUMAN (2-406): 3.77e-128: 385: 29.51		IBTK_HUMAN (1-1353): 0: 1106: 100.00
+	Sp
		252237 IF4A_SCHPO (21-407): 2.57e-178: 503: 75.97		BTB1_SCHPO (45-1337): 6.83e-139: 461: 19.08
+	Hs
		214077 DDX5_HUMAN (10-407): 3.86e-132: 394: 30.30		SPOP_HUMAN (707-933): 1.99e-70: 243: 24.23
+	Hs
		133777 DDX3X_HUMAN (2-406): 3.77e-128: 385: 29.51		SPOP_HUMAN (707-933): 1.99e-70: 243: 24.23
+	Hs
		214267 IF4A2_HUMAN (1-407): 2.49e-129: 380: 100.00		SPOP_HUMAN (707-933): 1.99e-70: 243: 24.23
+	Mm
		1118138 DDX3X_MOUSE (2-406): 6.76e-128: 385: 29.51		HERC2_MOUSE (16-249): 3.99e-19: 96.6: 15.90
+	Hs
		319745 IF4A3_HUMAN (3-407): 2.28e-130: 382: 67.65		HERC2_HUMAN (16-249): 6.62e-19: 95.9: 16.60