HitPredict

Interactor 1: HMGD (Q05783)
High mobility group protein D (HMG-D)
Gene: HMGD

Interactor 2: HMGZ (Q06943)
High mobility group protein Z (HMG-Z)
Gene: HMGZ

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	HMG_box~HMG_box
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0008301 - DNA binding, bending
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 112 Dm			1 111
+	Ce
		1171149 EGL13_CAEEL (2-108): 6.23e-36: 128: 19.27		EGL13_CAEEL (2-80): 1.88e-30: 113: 22.22
+	Dm
		121514 DICH_DROME (3-97): 7.67e-33: 119: 19.59		M9PFG6_DROME (2-88): 6e-32: 117: 25.84
+	Dm
		1174466 DICH_DROME (3-97): 7.67e-33: 119: 19.59		DICH_DROME (5-82): 1.04e-31: 116: 30.00
+	Hs
		336282 SOX14_HUMAN (2-86): 4.14e-33: 117: 22.99		SOX2_HUMAN (2-102): 9.5e-32: 115: 25.24
+	Hs
		833575 SOX3_HUMAN (3-92): 1.53e-30: 113: 21.74		SOX2_HUMAN (2-102): 9.5e-32: 115: 25.24
+	Hs
		872061 SOX2_HUMAN (2-103): 4.15e-31: 113: 21.15		SOX2_HUMAN (2-102): 9.5e-32: 115: 25.24
+	Dm
		120230 M9PFG6_DROME (3-87): 5.45e-32: 117: 19.54		M9PCZ7_DROME (4-77): 5.28e-29: 110: 28.95
+	Mm
		1049111 Q60I23_MOUSE (2-103): 6.57e-31: 113: 21.15		SOX8_MOUSE (2-111): 3.09e-30: 113: 17.86
+	Hs
		1413244 SOX7_HUMAN (3-112): 1.78e-32: 118: 15.57		SOX21_HUMAN (4-87): 3.6e-29: 107: 25.58
+	Hs
		833573 SOX3_HUMAN (3-92): 1.53e-30: 113: 21.74		SOX3_HUMAN (4-99): 4.64e-29: 110: 24.49
+	Hs
		872254 SOX2_HUMAN (2-103): 4.15e-31: 113: 21.15		SSRP1_HUMAN (4-77): 5.06e-28: 108: 51.32
+	Hs
		872125 SOX2_HUMAN (2-103): 4.15e-31: 113: 21.15		SOX8_HUMAN (2-111): 8.75e-28: 106: 16.81
+	Hs
		1401392 SOX17_HUMAN (3-86): 6.76e-31: 114: 17.44		CIC_HUMAN (3-107): 1.4e-26: 104: 21.50
+	Hs
		872653 SOX2_HUMAN (2-103): 4.15e-31: 113: 21.15		CIC_HUMAN (3-107): 1.4e-26: 104: 21.50
+	Hs
		141199 SOX2_HUMAN (2-103): 4.15e-31: 113: 21.15		SOX1_HUMAN (4-77): 6.79e-27: 103: 26.32
+	Dm
		1174467 DICH_DROME (3-97): 7.67e-33: 119: 19.59		HMG2_DROME (4-96): 3.34e-12: 62.9: 25.25