Protein: SOX3
Transcription factor SOX-3

Gene: SOX3
Organism: Homo sapiens
Interactions: 22
UniProt ID: P41225

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

833573

SOX3
Transcription factor SOX-3

1

20

High-throughput

0.647

High

833575

SOX2
Transcription factor SOX-2

1

19

Small-scale

0.618

High

209962

CRX
Cone-rod homeobox protein

2

20

High-throughput

0.606

High

833576

ATX1
Ataxin-1

2

14

High-throughput

0.606

High

833577

TRAF2
TNF receptor-associated factor 2

1

13

High-throughput

0.515

High

162916

TERT
Telomerase reverse transcriptase

1

1

High-throughput

0.501

High

169992

AURKA
Aurora kinase A

1

15

High-throughput

0.501

High

371377

MYC
Myc proto-oncogene protein

1

19

High-throughput

0.501

High

473839

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.501

High

767118

MERL
Merlin

1

12

High-throughput

0.501

High

833574

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

13

High-throughput

0.501

High

833579

TEAD2
Transcriptional enhancer factor TEF-4

1

5

High-throughput

0.501

High

833582

GLIS1
Zinc finger protein GLIS1

1

16

High-throughput

0.501

High

833583

NSD3
Histone-lysine N-methyltransferase NSD3

1

18

High-throughput

0.501

High

833584

GLIS2
Zinc finger protein GLIS2

1

18

High-throughput

0.501

High

833585

DACH1
Dachshund homolog 1

1

3

High-throughput

0.501

High

179155

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

20

Small-scale

0.479

High

833578

CUL3
Cullin-3

1

17

High-throughput

0.479

High

833580

TGIF1
Homeobox protein TGIF1

1

9

Small-scale

0.479

High

833586

TRRAP
Transformation/transcription domain-associated protein

1

7

Small-scale

0.479

High

833581

KLH22
Kelch-like protein 22

1

9

High-throughput

0.445

High


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Last updated: 11Aug2025