HitPredict

Interactor 1: RD23A (P54725)
UV excision repair protein RAD23 homolog A (HR23A) (hHR23A)
Gene: RAD23A

Interactor 2: PSMD4 (P55036)
26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10) (26S proteasome regulatory subunit S5A) (Antisecretory factor 1) (AF) (ASF) (Multiubiquitin chain-binding protein)
Gene: PSMD4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 29997244, 32296183, 14557549, 10488153, 12970176, 17408689, 14621999, 11827521, 19013454, 16105547, unassigned1913, 16990800, 20059542, unassigned1304
Identification Methods fluorescent resonance energy transfer, two hybrid, x-ray crystallography, pull down, affinity chromatography technology, split luciferase complementation, anti tag coimmunoprecipitation, nuclear magnetic resonance, two hybrid array, validated two hybrid and 2 others

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Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains UIM~ubiquitin, VWA_2~ubiquitin
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0031593 - polyubiquitin modification-dependent protein binding
and 1 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 363
Hs

1 377
+ Rn
+ Hs
+ At
+ At
+ At
+ At
+ Hs
+ Dm
+ Hs
+ Hs
+ Zm
+ Xl
+ Hs
+ Xl
+ Hs
+ Dm
+ Ce
+ At
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024