Interactor 1: PREX2 (Q70Z35)
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (P-Rex2) (PtdIns(3,4,5)-dependent Rac exchanger 2) (DEP domain-containing protein 2)
Gene: PREX2

Interactor 2: RHG18 (Q8N392)
Rho GTPase-activating protein 18 (MacGAP) (Rho-type GTPase-activating protein 18)
Gene: ARHGAP18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.571

The method score is based on:

Property Details
Experiments 32203420, unassigned2213
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005096 - GTPase activator activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0051056 - regulation of small GTPase mediated signal transduction
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 1606
Hs

1 663
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Last updated: 15 Jul 2024