HitPredict

Interactor 1: RN5A (Q05823)
2-5A-dependent ribonuclease (2-5A-dependent RNase) (EC 3.1.26.-) (Ribonuclease 4) (Ribonuclease L) (RNase L)
Gene: RNASEL

Interactor 2: RN5A (Q05823)
2-5A-dependent ribonuclease (2-5A-dependent RNase) (EC 3.1.26.-) (Ribonuclease 4) (Ribonuclease L) (RNase L)
Gene: RNASEL

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 24578532
Identification Methods x-ray crystallography, cross-linking study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~Ank_2, Ank_2~Ank_5, Ank_2~Pkinase, Ank_5~Ank_5, Ank_5~Pkinase, Pkinase~Pkinase, Pkinase~Ribonuc_2-5A, Ribonuc_2-5A~Ribonuc_2-5A
Common GO terms GO:0003723 - RNA binding
GO:0004521 - RNA endonuclease activity
GO:0004540 - RNA nuclease activity
GO:0004672 - protein kinase activity
GO:0005524 - ATP binding
and 16 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 741
Hs

1 741
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+ At
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+ At
+ Sc
+ At
+ Mm
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+ Mm
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Last updated: 11Aug2025