HitPredict

Interactor 1: FLNC (Q14315)
Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Interactor 2: OTUD1 (Q5VV17)
OTU domain-containing protein 1 (EC 3.4.19.12) (DUBA-7)
Gene: OTUD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.50	0.623

Property	Details
Experiments	35941131, 36357400, 36579465, 19615732
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2725 Hs			1 481
+	Hs
		966540 FLNC_HUMAN (1-2725): 0: 2507: 100.00		OTUD4_HUMAN (291-442): 7.99e-32: 131: 26.32
+	Hs
		598165 FLNA_HUMAN (167-2725): 0: 1226: 35.27		OTUD1_HUMAN (1-481): 1.17e-108: 332: 100.00
+	Hs
		261277 FLNB_HUMAN (146-2725): 0: 1198: 35.18		OTUD1_HUMAN (1-481): 1.17e-108: 332: 100.00
+	Hs
		598273 FLNA_HUMAN (167-2725): 0: 1226: 35.27		OTUD5_HUMAN (135-439): 1.37e-51: 185: 20.00
+	Dm
		1337379 FLNA_DROME (758-2724): 0: 1012: 33.19		TITIN_DROME (30-317): 1.46e-26: 116: 12.16
+	Hs
		211593 ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68		OTUD3_HUMAN (246-478): 1.23e-65: 218: 19.83
+	Dm
		574825 ACTN_DROME (1-386): 1.84e-105: 364: 25.90		TITIN_DROME (30-317): 1.46e-26: 116: 12.16
+	Hs
		59671 A4D1J9_HUMAN (1085-1244): 1.06e-13: 76.6: 28.79		OTUD1_HUMAN (1-481): 1.17e-108: 332: 100.00