HitPredict

Interactor 1: FLNC (Q14315)
Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Interactor 2: MEP50 (Q9BQA1)
Methylosome protein WDR77 (Androgen receptor cofactor p44) (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77) (p44/Mep50)
Gene: WDR77

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28977470
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 2725 Hs			1 342
+	Hs
		597996 FLNA_HUMAN (167-2725): 0: 1226: 35.27		LIS1_HUMAN (62-339): 9.49e-75: 238: 16.72
+	Hs
		598345 FLNA_HUMAN (167-2725): 0: 1226: 35.27		NLE1_HUMAN (114-333): 2.06e-53: 184: 18.05
+	Hs
		598240 FLNA_HUMAN (167-2725): 0: 1226: 35.27		POC1B_HUMAN (163-340): 1.65e-45: 163: 21.79
+	Hs
		598260 FLNA_HUMAN (167-2725): 0: 1226: 35.27		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		598040 FLNA_HUMAN (167-2725): 0: 1226: 35.27		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		261236 FLNB_HUMAN (146-2725): 0: 1198: 35.18		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		598209 FLNA_HUMAN (167-2725): 0: 1226: 35.27		WDR5B_HUMAN (3-106): 2.76e-09: 59.7: 7.90
+	Hs
		521604 ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		963405 SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		1301586 HMCN1_HUMAN (786-2707): 3.41e-96: 352: 11.24		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		362915 FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83		LIS1_HUMAN (62-339): 9.49e-75: 238: 16.72
+	Hs
		903137 SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		957555 PGBM_HUMAN (1306-2725): 4.84e-73: 276: 11.87		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		363003 FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		196937 FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83		PRP4_HUMAN (253-341): 3.86e-10: 62.8: 13.40