Interactor 1: ACHA7 (Q05941)
Neuronal acetylcholine receptor subunit alpha-7 (nAChR7) (Nicotinic acetylcholine receptor subunit alpha-7)
Gene: Chrna7

Interactor 2: ACHA7 (Q05941)
Neuronal acetylcholine receptor subunit alpha-7 (nAChR7) (Nicotinic acetylcholine receptor subunit alpha-7)
Gene: Chrna7

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.690

The method score is based on:

Property Details
Experiments 10627589
Identification Methods cosedimentation through density gradient, comigration in non denaturing gel electrophoresis, comigration in sds page
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Neur_chan_LBD~Neur_chan_LBD, Neur_chan_LBD~Neur_chan_memb, Neur_chan_memb~Neur_chan_memb
Common GO terms GO:0001540 - amyloid-beta binding
GO:0001666 - response to hypoxia
GO:0001988 - positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure
GO:0004888 - transmembrane signaling receptor activity
GO:0005216 - monoatomic ion channel activity
and 101 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 502
Rn

1 502
+ Rn
+ Hs
+ Hs
+ Gg
+ Gg
+ Gg
+ Dm
+ Dm
+ Hs
+ Mm
+ Rn
+ Hs
+ Rn
+ Gg
+ Hs
+ Gg
+ Mm
+ Rn

Service provided by Combinatics, Japan

Last updated: 11Aug2025