HitPredict

Interactor 1: RING1 (Q06587)
E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (Polycomb complex protein RING1) (RING finger protein 1) (RING-type E3 ubiquitin transferase RING1) (Really interesting new gene 1 protein)
Gene: RING1

Interactor 2: RING2 (Q99496)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3) (Protein DinG) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING finger protein BAP-1) (RING-type E3 ubiquitin transferase RING2)
Gene: RNF2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 24457600, 26496610, 22325352, 24981860, 16359901, 35271311, 35575683, 16943429, 15386022, 21596310
Identification Methods affinity chromatography technology, pull down, cross-linking study, anti tag coimmunoprecipitation, ion exchange chromatography, molecular sieving, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RAWUL~RAWUL, zf-C3HC4_2~zf-C3HC4_2
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0001739 - sex chromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 6 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Hs

1 336
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Last updated: 11Aug2025