Interactor 1: MCL1 (Q07820)
Induced myeloid leukemia cell differentiation protein Mcl-1 (Bcl-2-like protein 3) (Bcl2-L-3) (Bcl-2-related protein EAT/mcl1) (mcl1/EAT)
Gene: MCL1
Interactor 2: BMF (Q96LC9)
Bcl-2-modifying factor
Gene: BMF
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.79 | 1.00 | 0.892 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15721256, 16697956, 15694340, 32296183, unassigned1304 |
| Identification Methods | unspecified method, two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | BMF~Bcl-2 |
| Common GO terms | GO:0005741 - mitochondrial outer membrane GO:0005829 - cytosol GO:0010507 - negative regulation of autophagy GO:0043065 - positive regulation of apoptotic process |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
