HitPredict

Interactor 1: KLC1 (Q07866)
Kinesin light chain 1 (KLC 1)
Gene: KLC1

Interactor 2: SYNE4 (Q8N205)
Nesprin-4 (KASH domain-containing protein 4) (KASH4) (Nuclear envelope spectrin repeat protein 4)
Gene: SYNE4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 573 Hs			1 404
+	Hs
		1323892 KLC4_HUMAN (5-571): 9.65e-99: 314: 68.53		SYNE4_HUMAN (1-404): 0: 704: 100.00
+	Hs
		1323883 KLC2_HUMAN (5-571): 3.91e-94: 302: 68.43		SYNE4_HUMAN (1-404): 0: 704: 100.00
+	Mm
		1298751 KLC4_MOUSE (5-571): 3.82e-94: 302: 67.31		SYNE4_MOUSE (1-404): 0: 618: 65.35
+	Mm
		312237 KLC2_MOUSE (5-571): 6.84e-88: 285: 68.25		SYNE4_MOUSE (1-404): 0: 618: 65.35
+	Hs
		1257523 TMTC3_HUMAN (298-562): 2.64e-20: 97.4: 11.55		SYNE4_HUMAN (1-404): 0: 704: 100.00
+	Hs
		1242675 KLC3_HUMAN (376-569): 3.66e-13: 73.9: 17.82		SYNE4_HUMAN (1-404): 0: 704: 100.00
+	Mm
		312232 KLC1_MOUSE (336-567): 3.37e-19: 93.2: 22.55		SYNE4_MOUSE (1-404): 0: 618: 65.35
+	Mm
		1298750 KLC3_MOUSE (324-571): 2.73e-14: 77.4: 17.19		SYNE4_MOUSE (1-404): 0: 618: 65.35