HitPredict

Interactor 1: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Interactor 2: GPSM1 (Q86YR5)
G-protein-signaling modulator 1 (Activator of G-protein signaling 3)
Gene: GPSM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000132 - establishment of mitotic spindle orientation GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005938 - cell cortex GO:0032991 - protein-containing complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 2115 Hs			1 675
+	Hs
		946366 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		GPSM2_HUMAN (11-661): 7.43e-120: 374: 56.32
+	Hs
		174896 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		OGT1_HUMAN (1-587): 2.14e-70: 249: 15.83
+	Hs
		684450 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		STIP1_HUMAN (30-500): 5.21e-15: 80.4: 12.84
+	Hs
		684742 PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37		STIP1_HUMAN (30-500): 5.21e-15: 80.4: 12.84