Interactor 1: EMC2 (Q15006)
ER membrane protein complex subunit 2 (Tetratricopeptide repeat protein 35) (TPR repeat protein 35)
Gene: EMC2

Interactor 2: EMC6 (Q9BV81)
ER membrane protein complex subunit 6 (Transmembrane protein 93)
Gene: EMC6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 0.55 0.686

The method score is based on:

Property Details
Experiments 22119785, 28514442, 27342126, 33961781, 32439656
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0034975 - protein folding in endoplasmic reticulum
GO:0045050 - protein insertion into ER membrane by stop-transfer membrane-anchor sequence
GO:0071816 - tail-anchored membrane protein insertion into ER membrane
GO:0072546 - EMC complex
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024