HitPredict

Interactor 1: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Interactor 2: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	40437099
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006260 - DNA replication GO:0042393 - histone binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 709 Hs			1 425
+	Hs
		1065463 SSRP1_HUMAN (1-709): 0: 805: 100.00		NLE1_HUMAN (202-424): 2.44e-45: 165: 20.71
+	Hs
		1065153 SSRP1_HUMAN (1-709): 0: 805: 100.00		RBBP4_HUMAN (1-209): 1.71e-39: 148: 12.72
+	Hs
		964889 SSRP1_HUMAN (1-709): 0: 805: 100.00		WDR5_HUMAN (311-425): 1.4e-17: 85.2: 22.61
+	Dm
		1050908 SSRP1_DROME (1-702): 0: 683: 47.68		EBI_DROME (107-421): 2.2e-59: 207: 15.64
+	Hs
		1159015 HM20A_HUMAN (460-709): 5.94e-42: 157: 17.20		RBBP7_HUMAN (1-425): 1.15e-117: 351: 100.00
+	Hs
		1158968 CIC_HUMAN (461-706): 5.54e-35: 145: 17.48		RBBP7_HUMAN (1-425): 1.15e-117: 351: 100.00
+	Sc
		567724 RT106_YEAST (337-544): 2.21e-31: 129: 17.37		MSI1_YEAST (16-409): 3.49e-76: 244: 29.15
+	Hs
		1066505 HM20A_HUMAN (460-709): 5.94e-42: 157: 17.20		RBBP4_HUMAN (1-209): 1.71e-39: 148: 12.72
+	Hs
		1066453 CIC_HUMAN (461-706): 5.54e-35: 145: 17.48		RBBP4_HUMAN (1-209): 1.71e-39: 148: 12.72
+	Hs
		1149790 CIC_HUMAN (461-706): 5.54e-35: 145: 17.48		TAF5_HUMAN (7-255): 5.95e-37: 145: 17.32
+	Hs
		992919 CIC_HUMAN (461-706): 5.54e-35: 145: 17.48		RACK1_HUMAN (213-405): 5.45e-28: 114: 20.41
+	Hs
		659232 SP100_HUMAN (486-629): 1.52e-24: 111: 28.86		TAF5_HUMAN (7-255): 5.95e-37: 145: 17.32
+	Hs
		142298 SOX9_HUMAN (447-702): 2.04e-33: 136: 14.94		PEX7_HUMAN (230-404): 8.01e-25: 105: 19.13
+	Hs
		965173 CIC_HUMAN (461-706): 5.54e-35: 145: 17.48		WDR5_HUMAN (311-425): 1.4e-17: 85.2: 22.61
+	Hs
		687243 HMGB2_HUMAN (540-698): 5.44e-15: 76.3: 23.53		TAF5_HUMAN (7-255): 5.95e-37: 145: 17.32
+	Hs
		687210 HMGB2_HUMAN (540-698): 5.44e-15: 76.3: 23.53		RACK1_HUMAN (213-405): 5.45e-28: 114: 20.41
+	Hs
		687182 HMGB2_HUMAN (540-698): 5.44e-15: 76.3: 23.53		WDR5_HUMAN (311-425): 1.4e-17: 85.2: 22.61
+	Hs
		481188 HMGB1_HUMAN (543-634): 1.01e-14: 75.5: 34.04		WDR5_HUMAN (311-425): 1.4e-17: 85.2: 22.61