Interactor 1: RBBP4 (Q09028)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Interactor 2: CAF1A (Q13111)
Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-I p150) (hp150)
Gene: CHAF1A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 27705803, 33961781, 35271311, 37689310, 24981860, 17065558, 19498464, unassigned3799
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CAF1A~CAF1C_H4-bd, CAF1-p150_C2~WD40, CAF1A~WD40
Common GO terms GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0006260 - DNA replication
GO:0006281 - DNA repair
GO:0006334 - nucleosome assembly
and 3 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 425
Hs

1 956
+ Mm
+ Mm
+ Mm
+ Mm
+ Hs
+ Dm
+ Sc
+ Sp
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Sc
+ Dm

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Last updated: 11Aug2025