HitPredict

Interactor 1: RABE1 (Q15276)
Rab GTPase-binding effector protein 1 (Rabaptin-4) (Rabaptin-5) (Rabaptin-5alpha) (Renal carcinoma antigen NY-REN-17)
Gene: RABEP1

Interactor 2: RABE1 (Q15276)
Rab GTPase-binding effector protein 1 (Rabaptin-4) (Rabaptin-5) (Rabaptin-5alpha) (Renal carcinoma antigen NY-REN-17)
Gene: RABEP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.836

The method score is based on:

Property Details
Experiments 9524117, 15457209
Identification Methods two hybrid, pull down, x-ray crystallography, cross-linking study
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Rab5-bind~Rab5-bind
Common GO terms GO:0005096 - GTPase activator activity
GO:0005768 - endosome
GO:0005769 - early endosome
GO:0006893 - Golgi to plasma membrane transport
GO:0006897 - endocytosis
and 13 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 862
Hs

1 862
+ Rn
+ Hs
+ Mm
+ Hs
+ Xl
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024