HitPredict

Interactor 1: FBLN3 (Q12805)
EGF-containing fibulin-like extracellular matrix protein 1 (Extracellular protein S1-5) (Fibrillin-like protein) (Fibulin-3) (FIBL-3)
Gene: EFEMP1

Interactor 2: Q86UY0 (Q86UY0)
Thioredoxin domain-containing protein 5 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 46) (Thioredoxin-like protein p46)
Gene: TXNDC5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 493 Hs			1 360
+	Hs
		1086401 FBLN3_HUMAN (1-493): 3.1e-76: 249: 100.00		PDIA6_HUMAN (3-354): 1.28e-59: 200: 21.86
+	Hs
		1086425 FBLN3_HUMAN (1-493): 3.1e-76: 249: 100.00		TXND5_HUMAN (244-359): 2.43e-27: 113: 38.46
+	Hs
		1086421 FBLN3_HUMAN (1-493): 3.1e-76: 249: 100.00		DJC10_HUMAN (10-360): 3.82e-19: 90.7: 18.36
+	Hs
		717456 FBLN3_HUMAN (1-493): 3.1e-76: 249: 100.00		PDIA3_HUMAN (17-116): 1.27e-14: 76.7: 29.41
+	Hs
		452243 FBLN3_HUMAN (1-493): 3.1e-76: 249: 100.00		PDIA1_HUMAN (12-130): 2.64e-13: 72.6: 22.31
+	Hs
		566652 FBLN3_HUMAN (1-493): 3.1e-76: 249: 100.00		PDIA4_HUMAN (12-108): 3.71e-12: 69.5: 23.71
+	Hs
		1047542 NOTC2_HUMAN (3-386): 2.68e-17: 87.6: 10.63		PDIA5_HUMAN (7-235): 7.44e-48: 171: 21.98
+	Hs
		1312005 LTBP4_HUMAN (16-293): 9.59e-18: 89: 19.00		DJC10_HUMAN (10-360): 3.82e-19: 90.7: 18.36
+	Hs
		1312069 LTBP3_HUMAN (25-293): 5.38e-15: 80.1: 22.76		DJC10_HUMAN (10-360): 3.82e-19: 90.7: 18.36
+	Hs
		1312090 NOTC3_HUMAN (256-459): 1.91e-14: 78.4: 12.74		DJC10_HUMAN (10-360): 3.82e-19: 90.7: 18.36
+	Hs
		452164 TENX_HUMAN (4-176): 1.26e-18: 91.9: 11.01		PDIA1_HUMAN (12-130): 2.64e-13: 72.6: 22.31
+	Hs
		1312083 FBLN5_HUMAN (29-267): 3.19e-12: 70.3: 22.45		DJC10_HUMAN (10-360): 3.82e-19: 90.7: 18.36
+	Hs
		566580 FBN2_HUMAN (29-164): 1.48e-10: 66.3: 16.91		PDIA4_HUMAN (12-108): 3.71e-12: 69.5: 23.71