HitPredict

Interactor 1: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Interactor 2: INCE (Q9NQS7)
Inner centromere protein
Gene: INCENP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	30021884, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 918
+	Hs
		1087196 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		NIPBL_HUMAN (27-674): 3.82e-59: 223: 14.47
+	Hs
		918442 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		NIPBL_HUMAN (27-674): 3.82e-59: 223: 14.47
+	Hs
		918712 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		INCE_HUMAN (1-918): 8.99e-57: 213: 100.00
+	Hs
		1274470 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		BAZ2B_HUMAN (528-763): 2.18e-37: 154: 27.94
+	Hs
		1274476 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		MYH2_HUMAN (9-879): 4.99e-30: 131: 10.51
+	Hs
		724751 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		MYH9_HUMAN (4-746): 1.56e-26: 119: 10.08
+	Hs
		724951 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		MYH9_HUMAN (4-746): 1.56e-26: 119: 10.08
+	Hs
		241463 H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41		MYH9_HUMAN (4-746): 1.56e-26: 119: 10.08
+	Hs
		728463 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		MYH11_HUMAN (14-623): 5.06e-19: 95.3: 9.68
+	Hs
		725133 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		MYH10_HUMAN (9-659): 2.72e-18: 93: 8.72
+	Hs
		725214 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		MYH10_HUMAN (9-659): 2.72e-18: 93: 8.72
+	Hs
		241464 H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41		MYH10_HUMAN (9-659): 2.72e-18: 93: 8.72
+	Hs
		1129830 H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62		TITIN_HUMAN (34-608): 2.91e-17: 89.9: 14.97
+	Hs
		617962 H2B1O_HUMAN (1-126): 3.25e-54: 167: 99.21		TITIN_HUMAN (34-608): 2.91e-17: 89.9: 14.97
+	Hs
		1087299 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		TITIN_HUMAN (34-608): 2.91e-17: 89.9: 14.97
+	Hs
		1264778 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		TITIN_HUMAN (34-608): 2.91e-17: 89.9: 14.97
+	Hs
		883041 H2BFS_HUMAN (1-126): 1.26e-53: 166: 96.83		TITIN_HUMAN (34-608): 2.91e-17: 89.9: 14.97
+	Hs
		918561 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		TITIN_HUMAN (34-608): 2.91e-17: 89.9: 14.97
+	Hs
		1129870 H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62		MRCKB_HUMAN (528-797): 1.8e-11: 70.4: 18.03
+	Hs
		1274489 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		MRCKB_HUMAN (528-797): 1.8e-11: 70.4: 18.03