Protein: PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.4.13)

Gene: PRP16
Organism: Saccharomyces cerevisiae S288C
Interactions: 71
UniProt ID: P15938

Gene Ontology (top 5):
GO:0000350 - generation of catalytic spliceosome for second transesterification step
GO:0000378 - RNA exon ligation
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

590186

BRR2
Pre-mRNA-splicing helicase BRR2

3

19

Small-scale

0.872

High

590177

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

2

14

Small-scale

0.757

High

590174

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

14

High-throughput

0.618

High

590187

PRP8
Pre-mRNA-splicing factor 8

1

8

High-throughput

0.618

High

590189

NCBP1
Nuclear cap-binding protein complex subunit 1

1

4

High-throughput

0.618

High

590203

PRP17
Pre-mRNA-processing factor 17

1

19

High-throughput

0.618

High

590207

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

14

High-throughput

0.618

High

590211

CWC22
Pre-mRNA-splicing factor CWC22

1

3

High-throughput

0.618

High

590234

PRP46
Pre-mRNA-splicing factor PRP46

1

19

High-throughput

0.618

High

590176

ISY1
Pre-mRNA-splicing factor ISY1

2

4

Small-scale

0.584

High

590197

NTC20
Pre-mRNA-splicing factor NTC20

2

3

Small-scale

0.584

High

590212

PAP2
Poly(A) RNA polymerase protein 2

2

3

Small-scale

0.576

High

590215

NOP13
Nucleolar protein 13

1

11

High-throughput

0.515

High

590178

BUD31
Pre-mRNA-splicing factor BUD31

1

5

High-throughput

0.479

High

590179

PRP45
Pre-mRNA-processing protein 45

1

8

High-throughput

0.479

High

590180

YJU2
Splicing factor YJU2

1

4

High-throughput

0.479

High

590183

PRP19
Pre-mRNA-processing factor 19

1

19

High-throughput

0.479

High

590191

SN114
Pre-mRNA-splicing factor SNU114

1

11

High-throughput

0.479

High

590195

SLT11
Pre-mRNA-splicing factor SLT11

1

3

High-throughput

0.479

High

590202

MSL1
U2 small nuclear ribonucleoprotein B''

1

20

High-throughput

0.479

High

590209

SYF2
Pre-mRNA-splicing factor SYF2

1

3

High-throughput

0.479

High

590214

CWC25
Pre-mRNA-splicing factor CWC25

1

2

High-throughput

0.479

High

590219

CWC21
Pre-mRNA-splicing factor CWC21

1

2

High-throughput

0.479

High

590220

CEF1
Pre-mRNA-splicing factor CEF1

1

11

High-throughput

0.479

High

590221

CWC15
Pre-mRNA-splicing factor CWC15

1

2

High-throughput

0.479

High

590222

SYF1
Pre-mRNA-splicing factor SYF1

1

20

High-throughput

0.479

High

590223

SN309
Pre-mRNA-splicing factor SNT309

1

2

High-throughput

0.479

High

590227

NCBP2
Nuclear cap-binding protein subunit 2

1

9

High-throughput

0.479

High

590228

RU2A
U2 small nuclear ribonucleoprotein A'

1

7

High-throughput

0.479

High

590229

CWC2
Pre-mRNA-splicing factor CWC2

1

11

High-throughput

0.479

High

590230

YRA1
RNA annealing protein YRA1

1

6

High-throughput

0.479

High

590232

CLF1
Pre-mRNA-splicing factor CLF1

1

20

High-throughput

0.479

High

585466

KCY
Uridylate kinase

1

0

High-throughput

0.458

High

590198

KIC1
Serine/threonine-protein kinase KIC1

1

1

High-throughput

0.457

High

590217

UBC7
Ubiquitin-conjugating enzyme E2 7

1

5

High-throughput

0.457

High

522949

HSP71
Heat shock protein SSA1

1

7

High-throughput

0.445

High

543703

SSB1
Ribosome-associated molecular chaperone SSB1

1

9

High-throughput

0.445

High

590185

HSP7F
Heat shock protein homolog SSE1

1

11

High-throughput

0.445

High

590201

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.445

High

590224

DIB1
Spliceosomal protein DIB1

1

0

High-throughput

0.438

High

150145

THP2
THO complex subunit THP2

1

1

High-throughput

0.437

High

590175

HPR1
THO complex subunit HPR1

1

1

High-throughput

0.437

High

590181

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

590184

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

8

High-throughput

0.437

High

590188

MFT1
THO complex subunit MFT1

1

1

High-throughput

0.437

High

590194

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

1

High-throughput

0.437

High

590213

BRE5
UBP3-associated protein BRE5

1

7

High-throughput

0.437

High

590216

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

9

High-throughput

0.437

High

150228

YL462
Putative uncharacterized protein YLR462W

1

2

High-throughput

0.417

High

590190

UTP20
U3 small nucleolar RNA-associated protein 20

1

2

High-throughput

0.417

High

590193

CCL1
Cyclin CCL1

1

3

High-throughput

0.417

High

590205

RSF2
Respiration factor 2

1

2

High-throughput

0.417

High

590210

RBG2
Ribosome-interacting GTPase 2

1

4

High-throughput

0.417

High

590225

RRP44
Exosome complex exonuclease DIS3

1

3

High-throughput

0.417

High

590231

IQG1
Ras GTPase-activating-like protein IQG1

1

2

High-throughput

0.417

High

590208

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.269

Low

360939

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

High-throughput

0.249

Low

439554

LEU1
2-isopropylmalate synthase

1

0

High-throughput

0.249

Low

510952

IPB2
Protease B inhibitor 2

1

0

High-throughput

0.249

Low

590182

MLS1
Malate synthase 1

1

0

High-throughput

0.249

Low

590200

GDI1
Rab GDP-dissociation inhibitor

1

0

High-throughput

0.249

Low

150330

YP177
Putative uncharacterized protein YPR177C

1

0

High-throughput

0.238

Low

590192

YKH5
Uncharacterized protein YKL075C

1

0

High-throughput

0.238

Low

590196

UMP1
Proteasome maturation factor UMP1

1

0

High-throughput

0.238

Low

590199

MDM31
Mitochondrial distribution and morphology protein 31

1

0

High-throughput

0.238

Low

590204

MTHR1
Methylenetetrahydrofolate reductase 1

1

0

High-throughput

0.238

Low

590206

DOHH
Deoxyhypusine hydroxylase

1

0

High-throughput

0.238

Low

590218

YP067
Uncharacterized protein YPL067C

1

0

High-throughput

0.238

Low

590226

CRT10
Protein CRT10

1

0

High-throughput

0.238

Low

590233

APTH1
Acyl-protein thioesterase 1

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025