HitPredict

Interactor 1: PTPRN (Q16849)
Receptor-type tyrosine-protein phosphatase-like N (R-PTP-N) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3) (PTP IA-2) [Cleaved into: ICA512-N-terminal fragment (ICA512-NTF); ICA512-transmembrane fragment (ICA512-TMF); ICA512-cleaved cytosolic fragment (ICA512-CCF)]
Gene: PTPRN

Interactor 2: XPO5 (Q9HAV4)
Exportin-5 (Exp5) (Ran-binding protein 21)
Gene: XPO5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27432908
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 979 Hs			1 1204
+	Hs
		577067 PTPRA_HUMAN (217-970): 1.14e-111: 365: 17.77		XPO5_HUMAN (1-1204): 0: 1235: 100.00
+	Hs
		1088258 PTPRN_HUMAN (29-979): 0: 753: 100.00		TNPO3_HUMAN (3-854): 4.28e-136: 439: 13.56
+	Hs
		207945 PTPRN_HUMAN (29-979): 0: 753: 100.00		XPOT_HUMAN (21-846): 2.2e-106: 360: 13.84
+	Hs
		1088229 PTPRN_HUMAN (29-979): 0: 753: 100.00		XPO6_HUMAN (3-672): 6.35e-86: 305: 12.50
+	Hs
		874520 PTPRN_HUMAN (29-979): 0: 753: 100.00		XPO2_HUMAN (3-925): 1.33e-75: 272: 11.84
+	Hs
		207974 PTPR2_HUMAN (26-979): 0: 621: 40.60		XPOT_HUMAN (21-846): 2.2e-106: 360: 13.84
+	Hs
		162413 PTPRE_HUMAN (677-970): 6.27e-100: 330: 32.11		XPO1_HUMAN (3-923): 0: 589: 15.25
+	Hs
		162424 PTPRM_HUMAN (678-973): 7.59e-61: 228: 28.95		XPO1_HUMAN (3-923): 0: 589: 15.25
+	Hs
		163077 PTPRU_HUMAN (683-976): 3.8e-59: 223: 28.71		XPO1_HUMAN (3-923): 0: 589: 15.25
+	Hs
		577078 PTPRA_HUMAN (217-970): 1.14e-111: 365: 17.77		TNPO3_HUMAN (3-854): 4.28e-136: 439: 13.56
+	Hs
		617074 PTPRE_HUMAN (677-970): 6.27e-100: 330: 32.11		TNPO3_HUMAN (3-854): 4.28e-136: 439: 13.56
+	Hs
		207885 PTPRA_HUMAN (217-970): 1.14e-111: 365: 17.77		XPOT_HUMAN (21-846): 2.2e-106: 360: 13.84
+	Hs
		207891 PTPRE_HUMAN (677-970): 6.27e-100: 330: 32.11		XPOT_HUMAN (21-846): 2.2e-106: 360: 13.84
+	Hs
		577056 PTPRA_HUMAN (217-970): 1.14e-111: 365: 17.77		XPO6_HUMAN (3-672): 6.35e-86: 305: 12.50
+	Hs
		577005 PTPRA_HUMAN (217-970): 1.14e-111: 365: 17.77		XPO2_HUMAN (3-925): 1.33e-75: 272: 11.84
+	Hs
		617045 PTPRE_HUMAN (677-970): 6.27e-100: 330: 32.11		XPO2_HUMAN (3-925): 1.33e-75: 272: 11.84
+	Hs
		660841 PTPRM_HUMAN (678-973): 7.59e-61: 228: 28.95		XPO2_HUMAN (3-925): 1.33e-75: 272: 11.84
+	Hs
		874554 PTPRU_HUMAN (683-976): 3.8e-59: 223: 28.71		XPO2_HUMAN (3-925): 1.33e-75: 272: 11.84