HitPredict

Interactor 1: CDC16 (Q13042)
Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)
Gene: CDC16

Interactor 2: Q4KMX6 (Q4KMX6)
Anaphase-promoting complex subunit 7 (Cyclosome subunit 7)
Gene: ANAPC7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	ANAPC3~TPR_8, TPR_12~TPR_16, TPR_12~TPR_8
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 620 Hs			1 564
+	Hs
		1093079 CDC16_HUMAN (1-620): 2.43e-121: 374: 100.00		APC7_HUMAN (1-564): 6.4e-108: 336: 100.00
+	Hs
		186109 OGT1_HUMAN (3-449): 8.08e-56: 206: 10.82		APC7_HUMAN (1-564): 6.4e-108: 336: 100.00
+	Xl
		1231542 Q6DFI7_XENLA (1-620): 1.48e-116: 362: 88.60		Q6GQ04_XENLA (1-306): 1.58e-26: 116: 9.62
+	Sc
		486753 CDC16_YEAST (3-584): 2.44e-75: 258: 29.85		CDC23_YEAST (36-520): 2.83e-62: 217: 12.20
+	Sc
		597595 CDC23_YEAST (30-501): 2.82e-73: 248: 15.39		CDC23_YEAST (36-520): 2.83e-62: 217: 12.20
+	Hs
		1093078 CDC16_HUMAN (1-620): 2.43e-121: 374: 100.00		CDC23_HUMAN (240-545): 1.74e-14: 78.3: 12.31
+	Hs
		718554 CDC16_HUMAN (1-620): 2.43e-121: 374: 100.00		CDC27_HUMAN (14-195): 2.18e-13: 75.2: 10.94
+	Sp
		836486 CUT9_SCHPO (4-598): 5.85e-71: 243: 31.39		CUT9_SCHPO (8-520): 3.2e-53: 193: 13.36
+	At
		75112 APC7_ARATH (14-553): 7.3e-65: 224: 14.26		CDC16_ARATH (6-523): 2.31e-59: 208: 17.07
+	Hs
		185255 OGT1_HUMAN (3-449): 8.08e-56: 206: 10.82		OGT1_HUMAN (14-405): 8.82e-52: 193: 11.39
+	Hs
		718581 Q5T8C6_HUMAN (96-620): 7.21e-99: 311: 80.95		CDC27_HUMAN (14-195): 2.18e-13: 75.2: 10.94
+	Sc
		486745 CDC16_YEAST (3-584): 2.44e-75: 258: 29.85		CDC16_YEAST (213-534): 2.38e-15: 81.3: 12.11
+	At
		1354385 APC7_ARATH (14-553): 7.3e-65: 224: 14.26		CDC23_ARATH (151-552): 5.4e-23: 104: 9.66
+	Sc
		486772 CDC16_YEAST (3-584): 2.44e-75: 258: 29.85		CDC27_YEAST (372-544): 5.58e-09: 60.9: 9.61
+	Sp
		314369 CUT9_SCHPO (4-598): 5.85e-71: 243: 31.39		APC8_SCHPO (240-548): 4.05e-13: 74: 8.96
+	Sp
		522326 CUT9_SCHPO (4-598): 5.85e-71: 243: 31.39		APC3_SCHPO (2-266): 1.14e-12: 72.9: 12.82
+	Sc
		597608 CDC23_YEAST (30-501): 2.82e-73: 248: 15.39		CDC27_YEAST (372-544): 5.58e-09: 60.9: 9.61
+	At
		1320307 APC7_ARATH (14-553): 7.3e-65: 224: 14.26		CD27B_ARATH (44-335): 3.4e-15: 80.7: 10.93
+	At
		1057510 APC7_ARATH (14-553): 7.3e-65: 224: 14.26		CD27A_ARATH (15-281): 4.73e-15: 80.2: 14.82