Interactor 1: CDC27 (P30260)
Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)
Gene: CDC27
Interactor 2: CDC16 (Q13042)
Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)
Gene: CDC16
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 1.00 | 0.990 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12956947, 25306918, 27114510, 32152539, 32076268, 9628895, 10922056, 35271311, 35952650, 14657031, 9356466, 22193957, 17187060, 16364912, 21043528, 16648845, 26496610, 24100295, 28514442, 27173435 and 5 others
more... |
| Identification Methods | affinity chromatography technology, biochemical, two hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ANAPC3~ANAPC3, ANAPC3~TPR_12, TPR_1~TPR_12, ANAPC3~TPR_8, TPR_12~TPR_8 |
| Common GO terms | GO:0005654 - nucleoplasm GO:0005680 - anaphase-promoting complex GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol and 9 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025