HitPredict

Interactor 1: PSMD2 (Q13200)
26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2)
Gene: PSMD2

Interactor 2: DDI2 (Q5TDH0)
Protein DDI1 homolog 2 (EC 3.4.23.-)
Gene: DDI2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27114451
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PC_rep~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 908 Hs			1 399
+	Hs
		1098070 PSMD2_HUMAN (1-908): 0: 1290: 100.00		DDI1_HUMAN (1-392): 7.47e-148: 426: 70.75
+	Hs
		1098165 PSMD2_HUMAN (1-908): 0: 1290: 100.00		UBQL1_HUMAN (5-241): 5.8e-49: 176: 14.80
+	Hs
		1098159 PSMD2_HUMAN (1-908): 0: 1290: 100.00		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		1098150 PSMD2_HUMAN (1-908): 0: 1290: 100.00		UBQL4_HUMAN (8-241): 1.81e-44: 164: 14.59
+	Hs
		931508 PSMD2_HUMAN (1-908): 0: 1290: 100.00		RD23A_HUMAN (3-198): 2.37e-28: 116: 15.00
+	Hs
		1216196 PSMD1_HUMAN (59-845): 0: 790: 17.31		DDI2_HUMAN (1-399): 1.68e-162: 463: 100.00
+	Dm
		1487629 Q9VW54_DROME (3-906): 0: 1063: 60.65		Q9VWD9_DROME (5-241): 9.03e-44: 161: 16.39
+	Hs
		1356068 PSMD1_HUMAN (59-845): 0: 790: 17.31		DDI1_HUMAN (1-392): 7.47e-148: 426: 70.75
+	Dm
		1470298 Q9VW54_DROME (3-906): 0: 1063: 60.65		Q9VCD5_DROME (5-227): 2.19e-35: 133: 12.88
+	Sc
		803562 RPN1_YEAST (49-906): 0: 869: 37.71		DDI1_YEAST (3-395): 8.02e-93: 287: 30.92
+	Sp
		1017841 RPN1_SCHPO (8-905): 0: 1025: 47.67		DSK2_SCHPO (10-179): 8.19e-29: 117: 17.87
+	Sc
		803608 RPN1_YEAST (49-906): 0: 869: 37.71		DSK2_YEAST (19-213): 6.86e-31: 123: 15.49
+	Sc
		743981 RPN1_YEAST (49-906): 0: 869: 37.71		RAD23_YEAST (5-202): 3.9e-26: 110: 16.00
+	Hs
		1404607 PSMD1_HUMAN (59-845): 0: 790: 17.31		UBQL1_HUMAN (5-241): 5.8e-49: 176: 14.80
+	Hs
		1404601 PSMD1_HUMAN (59-845): 0: 790: 17.31		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		1404590 PSMD1_HUMAN (59-845): 0: 790: 17.31		UBQL4_HUMAN (8-241): 1.81e-44: 164: 14.59
+	Hs
		931585 PSMD1_HUMAN (59-845): 0: 790: 17.31		RD23A_HUMAN (3-198): 2.37e-28: 116: 15.00
+	Dm
		1464103 PSMD1_DROME (59-845): 0: 710: 17.07		Q9VWD9_DROME (5-241): 9.03e-44: 161: 16.39
+	Sc
		740125 RPN2_YEAST (59-841): 0: 679: 17.83		RAD23_YEAST (5-202): 3.9e-26: 110: 16.00