HitPredict

Interactor 1: PSA2 (Q27488)
Proteasome subunit alpha type-2 (Proteasome subunit alpha 2)
Gene: pas-2

Interactor 2: PBS5 (Q9XUV0)
Proteasome subunit pbs-5 (EC 3.4.25.1)
Gene: pbs-5

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.834

Property	Details
Experiments	12679813, 14704431, 11559592
Identification Methods	two hybrid, two hybrid pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms	GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 231 Ce			1 284
+	Hs
		656051 PSA6_HUMAN (2-231): 5.65e-102: 297: 32.77		PSB8_HUMAN (10-275): 1.11e-94: 282: 40.22
+	Dm
		771303 PSA2_DROME (2-231): 4.04e-109: 314: 60.52		PSA5_DROME (28-271): 5.06e-79: 241: 16.02
+	Dm
		771294 PSA2_DROME (2-231): 4.04e-109: 314: 60.52		Q7K148_DROME (37-279): 6.58e-78: 239: 44.08
+	Dm
		771302 PSA2_DROME (2-231): 4.04e-109: 314: 60.52		Q8T8V8_DROME (37-270): 2.75e-75: 234: 41.03
+	Hs
		656692 PSA6_HUMAN (2-231): 5.65e-102: 297: 32.77		PSB5_HUMAN (12-270): 1.49e-82: 250: 40.00
+	Hs
		656189 PSA6_HUMAN (2-231): 5.65e-102: 297: 32.77		PSA5_HUMAN (28-270): 4.2e-81: 246: 18.18
+	Sc
		619422 PSA2_YEAST (1-231): 1.88e-100: 293: 51.79		PSB5_YEAST (6-276): 1.43e-81: 249: 40.00
+	Hs
		656580 PSA6_HUMAN (2-231): 5.65e-102: 297: 32.77		PSB6_HUMAN (57-257): 7.31e-81: 245: 29.70
+	Dm
		47598 PSA2_DROME (2-231): 4.04e-109: 314: 60.52		A0AQH0_DROME (52-257): 6e-74: 227: 30.44
+	Dm
		184454 PSA2_DROME (2-231): 4.04e-109: 314: 60.52		O17311_DROME (62-264): 3.76e-72: 224: 28.57
+	Sc
		619405 PSA2_YEAST (1-231): 1.88e-100: 293: 51.79		PSB2_YEAST (40-250): 2.21e-80: 245: 26.76
+	Hs
		637663 PSA6_HUMAN (2-231): 5.65e-102: 297: 32.77		PSA2_HUMAN (29-271): 2.05e-77: 236: 14.58
+	Dm
		771324 PSA2_DROME (2-231): 4.04e-109: 314: 60.52		Q9VUJ1_DROME (67-264): 4.86e-70: 219: 28.28
+	Hs
		893733 PSA6_HUMAN (2-231): 5.65e-102: 297: 32.77		PSB7_HUMAN (26-263): 3.14e-73: 227: 26.78
+	Sc
		619459 PSA2_YEAST (1-231): 1.88e-100: 293: 51.79		PSB1_YEAST (57-266): 5.44e-74: 227: 26.76
+	Mt
		191406 PSA_METTH (2-231): 2.79e-96: 283: 35.75		PSB_METTH (63-271): 1.47e-71: 220: 31.43
+	Af
		191426 PSA_ARCFU (4-229): 3.11e-93: 275: 34.20		PSB_ARCFU (60-272): 9e-74: 226: 35.98
+	Dm
		47610 PSA5_DROME (3-231): 4.28e-92: 272: 31.67		A0AQH0_DROME (52-257): 6e-74: 227: 30.44
+	Mm
		1154361 PSA_METMP (2-231): 1.31e-93: 276: 33.62		PSB_METMP (60-273): 2.2e-69: 215: 25.93
+	Hs
		656102 PSA6_HUMAN (2-231): 5.65e-102: 297: 32.77		PSB9_HUMAN (57-251): 1.19e-18: 84: 32.14