HitPredict

Interactor 1: ATM (Q13315)
Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated)
Gene: ATM

Interactor 2: SCN3B (Q9NY72)
Sodium channel regulatory subunit beta-3
Gene: SCN3B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PI3_PI4_kinase~V-set
Common GO terms	GO:0005829 - cytosol GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 3056 Hs			1 215
+	Hs
		262223 ATM_HUMAN (1-3056): 0: 3845: 100.00		SCN2B_HUMAN (5-215): 2.01e-52: 169: 20.83
+	Hs
		1109521 ATR_HUMAN (1223-3056): 0: 1201: 20.34		SCN3B_HUMAN (1-215): 2.22e-69: 212: 100.00
+	Hs
		262227 ATR_HUMAN (1223-3056): 0: 1201: 20.34		SCN2B_HUMAN (5-215): 2.01e-52: 169: 20.83
+	Hs
		1109470 ATR_HUMAN (1223-3056): 0: 1201: 20.34		VSIG1_HUMAN (7-165): 1.08e-33: 125: 20.37
+	Hs
		1109489 ATR_HUMAN (1223-3056): 0: 1201: 20.34		VSIG2_HUMAN (10-164): 1.35e-32: 121: 19.88
+	Hs
		839389 MTOR_HUMAN (1846-3055): 0: 836: 16.65		SCN3B_HUMAN (1-215): 2.22e-69: 212: 100.00
+	Hs
		262211 MTOR_HUMAN (1846-3055): 0: 836: 16.65		SCN2B_HUMAN (5-215): 2.01e-52: 169: 20.83
+	Hs
		839310 MTOR_HUMAN (1846-3055): 0: 836: 16.65		VSIG1_HUMAN (7-165): 1.08e-33: 125: 20.37
+	Hs
		839342 MTOR_HUMAN (1846-3055): 0: 836: 16.65		VSIG2_HUMAN (10-164): 1.35e-32: 121: 19.88
+	Hs
		1452339 TRRAP_HUMAN (1874-3056): 0: 677: 12.97		SCN3B_HUMAN (1-215): 2.22e-69: 212: 100.00
+	Hs
		262289 SMG1_HUMAN (2626-2961): 7.75e-90: 331: 29.12		SCN2B_HUMAN (5-215): 2.01e-52: 169: 20.83
+	Hs
		1293894 SMG1_HUMAN (2626-2961): 7.75e-90: 331: 29.12		VSIG1_HUMAN (7-165): 1.08e-33: 125: 20.37