HitPredict

Interactor 1: ATR (Q13535)
Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1)
Gene: ATR

Interactor 2: SCN3B (Q9NY72)
Sodium channel regulatory subunit beta-3
Gene: SCN3B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.80	0.765

Property	Details
Experiments	28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PI3_PI4_kinase~V-set
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2644 Hs			1 215
+	Hs
		262227 ATR_HUMAN (1-2644): 0: 2972: 100.00		SCN2B_HUMAN (5-215): 2.01e-52: 169: 20.83
+	Hs
		1109470 ATR_HUMAN (1-2644): 0: 2972: 100.00		VSIG1_HUMAN (7-165): 1.08e-33: 125: 20.37
+	Hs
		1109489 ATR_HUMAN (1-2644): 0: 2972: 100.00		VSIG2_HUMAN (10-164): 1.35e-32: 121: 19.88
+	Hs
		839389 MTOR_HUMAN (756-2643): 0: 1253: 15.83		SCN3B_HUMAN (1-215): 2.22e-69: 212: 100.00
+	Hs
		262211 MTOR_HUMAN (756-2643): 0: 1253: 15.83		SCN2B_HUMAN (5-215): 2.01e-52: 169: 20.83
+	Hs
		839310 MTOR_HUMAN (756-2643): 0: 1253: 15.83		VSIG1_HUMAN (7-165): 1.08e-33: 125: 20.37
+	Hs
		1102276 ATM_HUMAN (772-2644): 0: 1164: 18.85		SCN3B_HUMAN (1-215): 2.22e-69: 212: 100.00
+	Hs
		839342 MTOR_HUMAN (756-2643): 0: 1253: 15.83		VSIG2_HUMAN (10-164): 1.35e-32: 121: 19.88
+	Hs
		262223 ATM_HUMAN (772-2644): 0: 1164: 18.85		SCN2B_HUMAN (5-215): 2.01e-52: 169: 20.83
+	Hs
		1452339 TRRAP_HUMAN (1161-2644): 0: 809: 13.19		SCN3B_HUMAN (1-215): 2.22e-69: 212: 100.00
+	Hs
		262289 SMG1_HUMAN (2136-2606): 1.13e-89: 330: 23.20		SCN2B_HUMAN (5-215): 2.01e-52: 169: 20.83
+	Hs
		1293894 SMG1_HUMAN (2136-2606): 1.13e-89: 330: 23.20		VSIG1_HUMAN (7-165): 1.08e-33: 125: 20.37