HitPredict

Interactor 1: SCN3B (Q9NY72)
Sodium channel regulatory subunit beta-3
Gene: SCN3B

Interactor 2: TRRAP (Q9Y4A5)
Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog)
Gene: TRRAP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PI3_PI4_kinase~V-set
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 3859
+	Hs
		1102276 SCN3B_HUMAN (1-215): 2.22e-69: 212: 100.00		ATM_HUMAN (2081-3858): 0: 1072: 12.80
+	Hs
		262223 SCN2B_HUMAN (5-215): 2.01e-52: 169: 20.83		ATM_HUMAN (2081-3858): 0: 1072: 12.80
+	Hs
		839389 SCN3B_HUMAN (1-215): 2.22e-69: 212: 100.00		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Hs
		262211 SCN2B_HUMAN (5-215): 2.01e-52: 169: 20.83		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Hs
		839310 VSIG1_HUMAN (7-165): 1.08e-33: 125: 20.37		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Hs
		839342 VSIG2_HUMAN (10-164): 1.35e-32: 121: 19.88		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Hs
		1109521 SCN3B_HUMAN (1-215): 2.22e-69: 212: 100.00		ATR_HUMAN (2569-3859): 0: 704: 15.07
+	Hs
		262227 SCN2B_HUMAN (5-215): 2.01e-52: 169: 20.83		ATR_HUMAN (2569-3859): 0: 704: 15.07
+	Hs
		1109470 VSIG1_HUMAN (7-165): 1.08e-33: 125: 20.37		ATR_HUMAN (2569-3859): 0: 704: 15.07
+	Hs
		1109489 VSIG2_HUMAN (10-164): 1.35e-32: 121: 19.88		ATR_HUMAN (2569-3859): 0: 704: 15.07
+	Hs
		262289 SCN2B_HUMAN (5-215): 2.01e-52: 169: 20.83		SMG1_HUMAN (3069-3820): 2.11e-109: 396: 14.75
+	Hs
		1293894 VSIG1_HUMAN (7-165): 1.08e-33: 125: 20.37		SMG1_HUMAN (3069-3820): 2.11e-109: 396: 14.75