HitPredict

Interactor 1: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Interactor 2: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	26186194, 28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 325 Hs			1 2229
+	Hs
		1102930 EIF3I_HUMAN (1-325): 3.6e-92: 279: 100.00		SRRM2_HUMAN (15-2006): 1.8e-37: 157: 9.78
+	Mm
		965395 WDR5_MOUSE (180-325): 4.05e-38: 139: 15.65		KMT2C_MOUSE (2-2044): 5.46e-69: 262: 9.65
+	Hs
		1102827 EIF3I_HUMAN (1-325): 3.6e-92: 279: 100.00		EIF3A_HUMAN (962-1409): 7.88e-26: 119: 14.63
+	Hs
		965097 WDR5_HUMAN (180-325): 4.05e-38: 139: 15.65		KMT2C_HUMAN (86-2064): 1.77e-62: 240: 9.54
+	Hs
		1102889 EIF3I_HUMAN (1-325): 3.6e-92: 279: 100.00		CIC_HUMAN (18-1410): 3.93e-17: 90.9: 8.32
+	Mm
		654190 EIF3I_MOUSE (1-325): 1.29e-91: 277: 99.39		EIF3A_MOUSE (883-1525): 9.61e-14: 79.5: 11.82
+	Hs
		1129693 SNR40_HUMAN (5-122): 5.03e-26: 107: 21.26		MDC1_HUMAN (92-1014): 1.36e-41: 171: 10.30
+	Hs
		1387648 SNR40_HUMAN (5-122): 5.03e-26: 107: 21.26		SRRM2_HUMAN (15-2006): 1.8e-37: 157: 9.78
+	Hs
		964938 WDR5_HUMAN (180-325): 4.05e-38: 139: 15.65		EIF3A_HUMAN (962-1409): 7.88e-26: 119: 14.63
+	Hs
		161490 POC1A_HUMAN (82-324): 1.04e-55: 187: 14.69		KMT2D_HUMAN (1599-2221): 1.48e-10: 69.3: 10.43
+	Hs
		845363 LIS1_HUMAN (1-82): 6.41e-21: 94.3: 25.61		SRRM2_HUMAN (15-2006): 1.8e-37: 157: 9.78
+	Hs
		1387512 SNR40_HUMAN (5-122): 5.03e-26: 107: 21.26		MINT_HUMAN (8-1813): 2.71e-32: 140: 6.95
+	Hs
		965173 WDR5_HUMAN (180-325): 4.05e-38: 139: 15.65		CIC_HUMAN (18-1410): 3.93e-17: 90.9: 8.32
+	Hs
		875607 WDR5_HUMAN (180-325): 4.05e-38: 139: 15.65		PRC2A_HUMAN (61-1403): 3.91e-16: 87.4: 8.67
+	Hs
		964950 WDR5_HUMAN (180-325): 4.05e-38: 139: 15.65		NCOA6_HUMAN (3-935): 5.4e-13: 77.4: 8.33
+	Hs
		1361892 SNR40_HUMAN (5-122): 5.03e-26: 107: 21.26		TITIN_HUMAN (59-1179): 4.76e-22: 107: 7.87
+	Hs
		161443 WDR5_HUMAN (180-325): 4.05e-38: 139: 15.65		KMT2D_HUMAN (1599-2221): 1.48e-10: 69.3: 10.43
+	Hs
		161486 WDR5B_HUMAN (180-325): 6.52e-34: 128: 13.61		KMT2D_HUMAN (1599-2221): 1.48e-10: 69.3: 10.43
+	Hs
		1247325 BRWD3_HUMAN (65-317): 2.09e-26: 112: 15.72		ZN469_HUMAN (45-1464): 1.11e-13: 79.7: 8.02
+	Hs
		319069 BRWD3_HUMAN (65-317): 2.09e-26: 112: 15.72		K0754_HUMAN (1370-1922): 8.54e-10: 66.8: 16.32