HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (p62)
Gene: SQSTM1

Interactor 2: NLRC5 (Q86WI3)
Protein NLRC5 (Caterpiller protein 16.1) (CLR16.1) (Nucleotide-binding oligomerization domain protein 27) (Nucleotide-binding oligomerization domain protein 4)
Gene: NLRC5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36126167
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 1866
+	Hs
		1108056 SQSTM_HUMAN (1-440): 0: 760: 100.00		NLRP3_HUMAN (908-1299): 5.12e-18: 92.9: 18.61
+	Hs
		1108171 SQSTM_HUMAN (1-440): 0: 760: 100.00		NOD2_HUMAN (985-1321): 5.66e-12: 73.3: 14.96
+	Hs
		1108296 SQSTM_HUMAN (1-440): 0: 760: 100.00		NOD1_HUMAN (846-1099): 2.61e-11: 70.9: 18.50
+	Hs
		947183 SQSTM_HUMAN (1-440): 0: 760: 100.00		NLRP6_HUMAN (1328-1556): 9.52e-10: 65.9: 15.56
+	Mm
		1225666 SQSTM_MOUSE (1-440): 0: 731: 90.72		NLRP3_MOUSE (905-1233): 6.48e-18: 92.9: 19.94
+	Hs
		854684 MIB1_HUMAN (105-233): 3.49e-43: 164: 25.19		RAGP1_HUMAN (1524-1792): 4.98e-09: 63.2: 25.50