HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (p62)
Gene: SQSTM1

Interactor 2: UB2E2 (Q96LR5)
Ubiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (UbcH8) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2)
Gene: UBE2E2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	39098523
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 201
+	Hs
		1108001 SQSTM_HUMAN (1-440): 0: 760: 100.00		UB2E3_HUMAN (1-201): 1.21e-83: 248: 81.64
+	Hs
		982182 SQSTM_HUMAN (1-440): 0: 760: 100.00		UB2D2_HUMAN (55-200): 9.65e-82: 240: 64.38
+	Hs
		957074 SQSTM_HUMAN (1-440): 0: 760: 100.00		UB2D3_HUMAN (55-200): 3.58e-80: 237: 63.70
+	Hs
		909315 SQSTM_HUMAN (1-440): 0: 760: 100.00		UB2E1_HUMAN (28-201): 3.78e-79: 236: 90.29
+	Hs
		1295603 MIB1_HUMAN (105-233): 3.49e-43: 164: 25.19		UB2D4_HUMAN (55-200): 2.57e-82: 242: 63.01
+	Hs
		982235 MIB1_HUMAN (105-233): 3.49e-43: 164: 25.19		UB2D2_HUMAN (55-200): 9.65e-82: 240: 64.38
+	Hs
		906699 MIB1_HUMAN (105-233): 3.49e-43: 164: 25.19		UB2D1_HUMAN (55-200): 3.67e-81: 239: 61.64
+	Hs
		957128 MIB1_HUMAN (105-233): 3.49e-43: 164: 25.19		UB2D3_HUMAN (55-200): 3.58e-80: 237: 63.70
+	Hs
		957783 MIB1_HUMAN (105-233): 3.49e-43: 164: 25.19		UBE2N_HUMAN (53-200): 1.92e-69: 210: 45.27
+	Hs
		982273 MIB2_HUMAN (106-264): 3.56e-23: 104: 26.09		UB2D2_HUMAN (55-200): 9.65e-82: 240: 64.38
+	Hs
		906733 MIB2_HUMAN (106-264): 3.56e-23: 104: 26.09		UB2D1_HUMAN (55-200): 3.67e-81: 239: 61.64
+	Hs
		957808 MIB2_HUMAN (106-264): 3.56e-23: 104: 26.09		UBE2N_HUMAN (53-200): 1.92e-69: 210: 45.27
+	Hs
		342819 HERC2_HUMAN (120-197): 2.61e-12: 71.3: 32.50		UB2D2_HUMAN (55-200): 9.65e-82: 240: 64.38
+	Hs
		342798 HERC2_HUMAN (120-197): 2.61e-12: 71.3: 32.50		UB2D1_HUMAN (55-200): 3.67e-81: 239: 61.64
+	Hs
		342813 HERC2_HUMAN (120-197): 2.61e-12: 71.3: 32.50		UB2D3_HUMAN (55-200): 3.58e-80: 237: 63.70
+	Hs
		982187 NBR1_HUMAN (80-184): 5.97e-10: 63.6: 24.78		UB2D2_HUMAN (55-200): 9.65e-82: 240: 64.38
+	Hs
		957080 NBR1_HUMAN (80-184): 5.97e-10: 63.6: 24.78		UB2D3_HUMAN (55-200): 3.58e-80: 237: 63.70
+	Hs
		342814 HERC2_HUMAN (120-197): 2.61e-12: 71.3: 32.50		UBE2N_HUMAN (53-200): 1.92e-69: 210: 45.27