HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (p62)
Gene: SQSTM1

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated protein 1 light chain 3 beta (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (Microtubule-associated proteins 1A/1B light chain 3B) (MAP1A/MAP1B LC3 B) (MAP1A/MAP1B light chain 3 B)
Gene: MAP1LC3B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.99 0.60 0.772

The method score is based on:

Property Details
Experiments 27791183, 28855742, 30853400, 29416008, 31286822, 31857374, 33545068, 34774801, 35205670, 39098523, 19250911, 23333919, 24023838, 24582747, 26413874, 28085563, 26524528, 27554286, 27158844, 29426817 and 28 others

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Identification Methods affinity chromatography technology, pull down, proximity labelling technology, two hybrid, x-ray crystallography, unspecified method, tandem affinity purification, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, validated two hybrid and 6 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000423 - mitophagy
GO:0005739 - mitochondrion
GO:0005776 - autophagosome
GO:0005829 - cytosol
GO:0006914 - autophagy
and 2 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 440
Hs

1 125
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Last updated: 11Aug2025