HitPredict

Interactor 1: TBB3 (Q13509)
Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)
Gene: TUBB3

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34273398
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 450 Hs			1 1620
+	Hs
		457768 TBB5_HUMAN (1-429): 0: 704: 93.94		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		1415133 TBB2B_HUMAN (1-430): 0: 703: 93.72		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		997563 TBB4B_HUMAN (1-427): 0: 703: 93.91		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		439616 TBB5_HUMAN (1-429): 0: 704: 93.94		INSR_HUMAN (973-1436): 1e-112: 392: 34.25
+	Hs
		465633 TBB6_HUMAN (1-446): 0: 700: 92.38		IGF1R_HUMAN (1037-1385): 8.56e-111: 386: 39.77
+	Hs
		572922 TBB3_HUMAN (1-450): 0: 723: 100.00		INSRR_HUMAN (1082-1384): 2.39e-70: 262: 43.46
+	Hs
		411884 TBB3_HUMAN (1-450): 0: 723: 100.00		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		411197 TBB5_HUMAN (1-429): 0: 704: 93.94		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		411723 TBB4B_HUMAN (1-427): 0: 703: 93.91		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		412542 TBB2B_HUMAN (1-430): 0: 703: 93.72		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		412535 TBB6_HUMAN (1-446): 0: 700: 92.38		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		1157055 TBB6_HUMAN (1-446): 0: 700: 92.38		NTRK3_HUMAN (1093-1375): 2.7e-59: 223: 39.03
+	Hs
		541664 TBB6_HUMAN (1-446): 0: 700: 92.38		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07
+	Hs
		407966 TBB4A_HUMAN (1-427): 0: 698: 93.21		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07