Interactor 1: CDC7 (P06243)
Cell division control protein 7 (EC 2.7.11.1)
Gene: CDC7

Interactor 2: DBF4 (P32325)
DDK kinase regulatory subunit DBF4 (Dumbbell forming protein 4)
Gene: DBF4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.993

The method score is based on:

Property Details
Experiments 8474449, 10964916, 8066465, 24566989, 24532715, 8943332, 10508166, 8657159, 25602519, 24875188, 26682552, 31519521, 34387546, 19013276, 19822727, 35296675, 37968396, 20489023, 21036905, 9790600 and 9 others

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Identification Methods two hybrid, biochemical, coimmunoprecipitation, pull down, affinity chromatography technology, enzymatic study, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~zf-DBF
Common GO terms GO:0000775 - chromosome, centromeric region
GO:0000785 - chromatin
GO:0001100 - negative regulation of exit from mitosis
GO:0005634 - nucleus
GO:0005813 - centrosome
and 8 others

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Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 507
Sc

1 704
+ Sc
+ Sp
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024