HitPredict

Interactor 1: LAPM5 (Q13571)
Lysosomal-associated transmembrane protein 5 (Lysosomal-associated multitransmembrane protein 5) (Retinoic acid-inducible E3 protein)
Gene: LAPTM5

Interactor 2: NED4L (Q96PU5)
E3 ubiquitin-protein ligase NEDD4-like (EC 2.3.2.26) (EC 2.3.2.36) (HECT-type E3 ubiquitin transferase NED4L) (NEDD4.2) (Nedd4-2)
Gene: NEDD4L

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.678

Property	Details
Experiments	37156795, 33961781, 15231748
Identification Methods	affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 262 Hs			1 975
+	Hs
		861597 LAPM5_HUMAN (1-262): 2.04e-151: 424: 100.00		NEDD4_HUMAN (100-975): 0: 801: 61.35
+	Hs
		861645 Q5TBB8_HUMAN (1-262): 2.04e-151: 424: 100.00		NEDD4_HUMAN (100-975): 0: 801: 61.35
+	Hs
		1110928 LAPM5_HUMAN (1-262): 2.04e-151: 424: 100.00		ITCH_HUMAN (9-972): 0: 795: 32.96
+	Mm
		861877 LAPM5_MOUSE (1-262): 4.29e-144: 405: 79.01		NEDD4_MOUSE (12-975): 0: 808: 55.08
+	Hs
		1110932 LAPM5_HUMAN (1-262): 2.04e-151: 424: 100.00		WWP1_HUMAN (1-972): 0: 787: 32.96
+	Hs
		132018 LAPM5_HUMAN (1-262): 2.04e-151: 424: 100.00		WWP2_HUMAN (213-972): 0: 732: 36.95
+	Hs
		1110935 LAPM5_HUMAN (1-262): 2.04e-151: 424: 100.00		SMUF2_HUMAN (21-418): 1.09e-33: 141: 21.20