HitPredict

Interactor 1: WWP2 (O00308)
NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (Atrophin-1-interacting protein 2) (AIP2) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2)
Gene: WWP2

Interactor 2: LAPM5 (Q13571)
Lysosomal-associated transmembrane protein 5 (Lysosomal-associated multitransmembrane protein 5) (Retinoic acid-inducible E3 protein)
Gene: LAPTM5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35842443, 37156795
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 870 Hs			1 262
+	Hs
		1110928 ITCH_HUMAN (1-870): 0: 899: 53.91		LAPM5_HUMAN (1-262): 2.04e-151: 424: 100.00
+	Hs
		1110932 WWP1_HUMAN (1-870): 0: 883: 58.27		LAPM5_HUMAN (1-262): 2.04e-151: 424: 100.00
+	Hs
		1110929 NED4L_HUMAN (5-867): 0: 786: 32.04		LAPM5_HUMAN (1-262): 2.04e-151: 424: 100.00
+	Hs
		861597 NEDD4_HUMAN (90-867): 0: 728: 36.26		LAPM5_HUMAN (1-262): 2.04e-151: 424: 100.00
+	Hs
		861645 NEDD4_HUMAN (90-867): 0: 728: 36.26		Q5TBB8_HUMAN (1-262): 2.04e-151: 424: 100.00
+	Mm
		861877 NEDD4_MOUSE (14-470): 1e-54: 206: 16.08		LAPM5_MOUSE (1-262): 4.29e-144: 405: 79.01
+	Hs
		1110935 SMUF2_HUMAN (1-331): 4.63e-36: 148: 15.73		LAPM5_HUMAN (1-262): 2.04e-151: 424: 100.00