HitPredict

Interactor 1: AGAP2 (Q3UHD9)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (Phosphatidylinositol 3-kinase enhancer) (PIKE)
Gene: AGAP2

Interactor 2: KCC2G (Q923T9)
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)
Gene: Camk2g

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	28706196
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~Pkinase, Pkinase~Ras
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1186 Mm			1 529
+	Mm
		659450 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		KCC2B_MOUSE (1-529): 0: 584: 81.18
+	Mm
		1112593 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		KCC2D_MOUSE (1-529): 0: 555: 78.45
+	Mm
		515228 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		KCC2A_MOUSE (1-526): 0: 536: 75.67
+	Rn
		506765 AGAP2_RAT (1-1186): 0: 1019: 99.07		KCC2A_RAT (1-526): 0: 536: 75.67
+	Mm
		1112653 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		DCLK1_MOUSE (11-272): 9.08e-66: 228: 44.15
+	Hs
		1357913 GIT1_HUMAN (932-1139): 4.84e-72: 258: 32.88		KCC2A_HUMAN (1-526): 0: 536: 75.86
+	Rn
		506783 GIT1_RAT (932-1139): 1.69e-71: 257: 32.88		KCC2A_RAT (1-526): 0: 536: 75.67
+	Hs
		1050113 GIT2_HUMAN (932-1139): 1.58e-73: 262: 31.98		KCC4_HUMAN (10-304): 9.1e-73: 240: 43.43
+	Hs
		1083229 GIT1_HUMAN (932-1139): 4.84e-72: 258: 32.88		KCC4_HUMAN (10-304): 9.1e-73: 240: 43.43