HitPredict

Interactor 1: CAND1 (G5ED41)
Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1)
Gene: cand-1

Interactor 2: CUL4 (Q17392)
Cullin-4 (CUL-4)
Gene: cul-4

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.713

Property	Details
Experiments	20659444
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Cullin~TIP120
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1274 Ce			1 840
+	Hs
		1114920 CAND1_HUMAN (2-1263): 0: 768: 36.00		CUL4A_HUMAN (51-840): 0: 808: 31.61
+	Hs
		1115282 CAND1_HUMAN (2-1263): 0: 768: 36.00		CUL4B_HUMAN (53-840): 0: 804: 31.44
+	Hs
		1113580 CAND1_HUMAN (2-1263): 0: 768: 36.00		CUL3_HUMAN (76-840): 0: 757: 27.86
+	Hs
		273190 CAND2_HUMAN (2-1269): 0: 720: 32.89		CUL4B_HUMAN (53-840): 0: 804: 31.44
+	Hs
		1112580 CAND1_HUMAN (2-1263): 0: 768: 36.00		CUL1_HUMAN (106-840): 0: 714: 22.17
+	Mm
		1253432 CAND1_MOUSE (2-1263): 0: 764: 35.84		CUL1_MOUSE (106-840): 0: 714: 22.17
+	Hs
		273189 CAND2_HUMAN (2-1269): 0: 720: 32.89		CUL3_HUMAN (76-840): 0: 757: 27.86
+	Ce
		111413 CAND1_CAEEL (1-1274): 0: 759: 100.00		CUL3_CAEEL (98-840): 0: 683: 24.87
+	Mm
		1253452 CAND2_MOUSE (3-1269): 0: 728: 32.53		CUL1_MOUSE (106-840): 0: 714: 22.17
+	Hs
		273188 CAND2_HUMAN (2-1269): 0: 720: 32.89		CUL1_HUMAN (106-840): 0: 714: 22.17
+	Hs
		1112901 CAND1_HUMAN (2-1263): 0: 768: 36.00		CUL2_HUMAN (116-840): 0: 661: 21.80
+	At
		1318213 CAND1_ARATH (1-1260): 0: 657: 29.67		CUL4_ARATH (67-840): 0: 755: 31.23
+	Dm
		1304391 CAND1_DROME (4-1266): 0: 679: 34.93		Q8IP45_DROME (32-840): 0: 729: 25.93
+	Ce
		111411 CAND1_CAEEL (1-1274): 0: 759: 100.00		CUL1_CAEEL (113-840): 0: 642: 23.09
+	Ce
		111412 CAND1_CAEEL (1-1274): 0: 759: 100.00		CUL2_CAEEL (98-840): 0: 612: 21.20
+	At
		1318216 CAND1_ARATH (1-1260): 0: 657: 29.67		CUL1_ARATH (111-840): 0: 710: 24.80
+	Ce
		111415 CAND1_CAEEL (1-1274): 0: 759: 100.00		CUL6_CAEEL (117-840): 0: 589: 21.89
+	Dm
		1173428 CAND1_DROME (4-1266): 0: 679: 34.93		CUL1_DROME (104-840): 0: 669: 22.59
+	Hs
		1291113 CAND1_HUMAN (2-1263): 0: 768: 36.00		CUL5_HUMAN (106-840): 0: 560: 18.31
+	Ce
		111416 CAND1_CAEEL (1-1274): 0: 759: 100.00		CUL5_CAEEL (118-840): 0: 567: 18.28