HitPredict

Interactor 1: CAND1 (Q8L5Y6)
Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (AtCAND1) (Protein ENHANCER OF TIR1-1 AUXIN RESISTANCE 2) (Protein HEMIVENATA)
Gene: CAND1

Interactor 2: CUL4 (Q8LGH4)
Cullin-4 (AtCUL4)
Gene: CUL4

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.80	0.662

Property	Details
Experiments	16844902
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Cullin~TIP120
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1219 At			1 792
+	Hs
		1115282 CAND1_HUMAN (2-1219): 0: 794: 42.73		CUL4B_HUMAN (29-792): 0: 923: 55.95
+	Hs
		1114920 CAND1_HUMAN (2-1219): 0: 794: 42.73		CUL4A_HUMAN (34-792): 0: 914: 55.79
+	Hs
		273190 CAND2_HUMAN (2-1219): 0: 736: 38.14		CUL4B_HUMAN (29-792): 0: 923: 55.95
+	Hs
		1113580 CAND1_HUMAN (2-1219): 0: 794: 42.73		CUL3_HUMAN (60-792): 0: 833: 38.63
+	Dm
		1304391 CAND1_DROME (4-1219): 0: 720: 38.83		Q8IP45_DROME (8-792): 0: 862: 35.36
+	Hs
		273189 CAND2_HUMAN (2-1219): 0: 736: 38.14		CUL3_HUMAN (60-792): 0: 833: 38.63
+	At
		1318216 CAND1_ARATH (1-1219): 0: 803: 100.00		CUL1_ARATH (85-792): 0: 757: 32.17
+	Hs
		1112580 CAND1_HUMAN (2-1219): 0: 794: 42.73		CUL1_HUMAN (93-792): 0: 757: 29.37
+	Mm
		1253432 CAND1_MOUSE (2-1219): 0: 793: 42.41		CUL1_MOUSE (93-792): 0: 757: 29.37
+	Mm
		1253452 CAND2_MOUSE (3-1219): 0: 754: 38.12		CUL1_MOUSE (93-792): 0: 757: 29.37
+	Hs
		1112901 CAND1_HUMAN (2-1219): 0: 794: 42.73		CUL2_HUMAN (91-792): 0: 716: 26.44
+	Hs
		273188 CAND2_HUMAN (2-1219): 0: 736: 38.14		CUL1_HUMAN (93-792): 0: 757: 29.37
+	Dm
		1173428 CAND1_DROME (4-1219): 0: 720: 38.83		CUL1_DROME (93-792): 0: 706: 29.15
+	Hs
		1291113 CAND1_HUMAN (2-1219): 0: 794: 42.73		CUL5_HUMAN (92-792): 0: 609: 25.68
+	Ce
		111413 CAND1_CAEEL (1-1219): 0: 588: 28.73		CUL3_CAEEL (75-792): 0: 739: 32.56
+	Ce
		111411 CAND1_CAEEL (1-1219): 0: 588: 28.73		CUL1_CAEEL (80-792): 0: 687: 26.85
+	Ce
		111412 CAND1_CAEEL (1-1219): 0: 588: 28.73		CUL2_CAEEL (63-792): 0: 665: 24.53
+	Ce
		111414 CAND1_CAEEL (1-1219): 0: 588: 28.73		CUL4_CAEEL (6-792): 0: 662: 30.75
+	Ce
		111415 CAND1_CAEEL (1-1219): 0: 588: 28.73		CUL6_CAEEL (93-792): 0: 624: 27.09
+	Ce
		111416 CAND1_CAEEL (1-1219): 0: 588: 28.73		CUL5_CAEEL (92-792): 0: 565: 24.32