HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: PHRF1 (Q9P1Y6)
PHD and RING finger domain-containing protein 1
Gene: PHRF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37788672
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0016567 - protein ubiquitination
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 1649
+	Hs
		1113124 CUL3_HUMAN (1-768): 0: 943: 100.00		CHD4_HUMAN (16-273): 2.11e-44: 179: 23.72
+	Hs
		1088330 CUL3_HUMAN (1-768): 0: 943: 100.00		CHD3_HUMAN (29-273): 3.05e-42: 172: 23.32
+	Hs
		1114088 CUL3_HUMAN (1-768): 0: 943: 100.00		UHRF1_HUMAN (140-278): 8.15e-28: 124: 28.87
+	Hs
		833734 CUL3_HUMAN (1-768): 0: 943: 100.00		KDM5C_HUMAN (169-249): 3.79e-24: 113: 33.33
+	Hs
		1114056 CUL3_HUMAN (1-768): 0: 943: 100.00		UHRF2_HUMAN (186-278): 3.67e-23: 109: 34.38
+	Hs
		1113373 CUL3_HUMAN (1-768): 0: 943: 100.00		MUC17_HUMAN (245-1123): 1.31e-17: 92.1: 9.33
+	Hs
		161463 CUL3_HUMAN (1-768): 0: 943: 100.00		KMT2D_HUMAN (451-1321): 3.88e-13: 77.5: 8.84
+	Hs
		1113742 CUL3_HUMAN (1-768): 0: 943: 100.00		KMT2C_HUMAN (129-244): 5.64e-12: 73.4: 24.59
+	Hs
		1114821 CUL4A_HUMAN (10-768): 0: 801: 38.32		CHD4_HUMAN (16-273): 2.11e-44: 179: 23.72
+	Hs
		1115018 CUL4A_HUMAN (10-768): 0: 801: 38.32		SCAFB_HUMAN (848-1646): 2.49e-44: 179: 19.58
+	Hs
		1115369 CUL4B_HUMAN (5-768): 0: 796: 36.77		UHRF2_HUMAN (186-278): 3.67e-23: 109: 34.38
+	Hs
		1112671 CUL1_HUMAN (18-768): 0: 709: 30.57		UHRF1_HUMAN (140-278): 8.15e-28: 124: 28.87
+	Sp
		152907 CUL4_SCHPO (7-767): 0: 579: 25.35		LID2_SCHPO (139-262): 2.44e-18: 94.1: 25.39