HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: RRBP1 (Q9P2E9)
Ribosome-binding protein 1 (180 kDa ribosome receptor homolog) (RRp) (ES/130-related protein) (Ribosome receptor protein)
Gene: RRBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 1410
+	Hs
		1113228 CUL3_HUMAN (1-768): 0: 943: 100.00		COOA1_HUMAN (37-397): 3.36e-44: 178: 10.44
+	Hs
		772788 CUL3_HUMAN (1-768): 0: 943: 100.00		MYH9_HUMAN (744-1410): 4.71e-30: 132: 15.58
+	Hs
		438030 CUL3_HUMAN (1-768): 0: 943: 100.00		CO5A2_HUMAN (184-580): 3.96e-26: 119: 9.75
+	Hs
		471589 CUL3_HUMAN (1-768): 0: 943: 100.00		CO4A2_HUMAN (278-580): 5.81e-24: 112: 11.55
+	Hs
		384313 CUL3_HUMAN (1-768): 0: 943: 100.00		CO4A1_HUMAN (191-547): 5.18e-23: 109: 10.88
+	Hs
		1114049 CUL3_HUMAN (1-768): 0: 943: 100.00		COLA1_HUMAN (38-297): 1.04e-19: 98.1: 7.30
+	Hs
		157340 CUL3_HUMAN (1-768): 0: 943: 100.00		CTRO_HUMAN (486-1105): 4.34e-19: 96.6: 11.58
+	Hs
		1036620 CUL3_HUMAN (1-768): 0: 943: 100.00		CO7A1_HUMAN (308-589): 1.36e-15: 85: 10.99
+	Hs
		465961 CUL3_HUMAN (1-768): 0: 943: 100.00		CO1A2_HUMAN (37-226): 1.97e-14: 81.1: 10.14
+	Hs
		773179 CUL3_HUMAN (1-768): 0: 943: 100.00		MYH10_HUMAN (1041-1410): 5e-14: 80: 14.32
+	Hs
		384253 CUL3_HUMAN (1-768): 0: 943: 100.00		CO2A1_HUMAN (40-314): 2.75e-13: 77.3: 7.60
+	Hs
		1113389 CUL3_HUMAN (1-768): 0: 943: 100.00		MRCKG_HUMAN (1161-1408): 3.6e-13: 76.9: 17.05
+	Hs
		384151 CUL3_HUMAN (1-768): 0: 943: 100.00		CO1A1_HUMAN (34-326): 3.87e-13: 76.9: 9.12
+	Hs
		1114388 CUL3_HUMAN (1-768): 0: 943: 100.00		MYO5C_HUMAN (526-874): 5.98e-11: 69.6: 10.36
+	Hs
		1114669 CUL3_HUMAN (1-768): 0: 943: 100.00		TNR6B_HUMAN (108-628): 3.88e-10: 66.9: 12.65
+	Hs
		1113529 CUL3_HUMAN (1-768): 0: 943: 100.00		MYH14_HUMAN (1026-1394): 8.33e-09: 62.7: 16.71
+	Hs
		773180 CUL4A_HUMAN (10-768): 0: 801: 38.32		MYH10_HUMAN (1041-1410): 5e-14: 80: 14.32
+	Hs
		772787 CUL1_HUMAN (18-768): 0: 709: 30.57		MYH9_HUMAN (744-1410): 4.71e-30: 132: 15.58
+	Hs
		773178 CUL1_HUMAN (18-768): 0: 709: 30.57		MYH10_HUMAN (1041-1410): 5e-14: 80: 14.32
+	Hs
		1112799 CUL1_HUMAN (18-768): 0: 709: 30.57		TNR6B_HUMAN (108-628): 3.88e-10: 66.9: 12.65