Protein: PPIG
Peptidyl-prolyl cis-trans isomerase G (PPIase G) (Peptidyl-prolyl isomerase G) (EC 5.2.1.8) (CASP10) (Clk-associating RS-cyclophilin) (CARS-Cyp) (CARS-cyclophilin) (SR-cyclophilin) (SR-cyp) (SRcyp) (Cyclophilin G) (Rotamase G)

Gene: PPIG
Organism: Homo sapiens
Interactions: 123
UniProt ID: Q13427

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1104945

TRA2A
Transformer-2 protein homolog alpha

3

2

High-throughput

0.861

High

1104951

RNPS1
RNA-binding protein with serine-rich domain 1

3

7

High-throughput

0.839

High

1104948

RBM39
RNA-binding protein 39

2

6

High-throughput

0.831

High

1099059

SRSF5
Serine/arginine-rich splicing factor 5

2

9

High-throughput

0.776

High

1104976

SNIP1
Smad nuclear-interacting protein 1

4

2

High-throughput

0.694

High

256615

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

3

High-throughput

0.691

High

478025

SNRPA
U1 small nuclear ribonucleoprotein A

1

7

High-throughput

0.691

High

1016421

SRSF3
Serine/arginine-rich splicing factor 3

1

13

High-throughput

0.691

High

1051461

SRS11
Serine/arginine-rich splicing factor 11

1

5

High-throughput

0.691

High

1060963

SRSF1
Serine/arginine-rich splicing factor 1

1

11

High-throughput

0.691

High

1061977

SRSF4
Serine/arginine-rich splicing factor 4

1

7

High-throughput

0.691

High

1099326

SRSF6
Serine/arginine-rich splicing factor 6

1

9

High-throughput

0.691

High

1104955

SRSF7
Serine/arginine-rich splicing factor 7

1

8

High-throughput

0.691

High

1104956

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

11

High-throughput

0.691

High

1104984

PABP5
Polyadenylate-binding protein 5

1

2

High-throughput

0.691

High

1104990

PININ
Pinin

3

3

Small-scale

0.679

High

1104966

ZCH18
Zinc finger CCCH domain-containing protein 18

3

9

High-throughput

0.667

High

1104953

PCBP1
Poly(rC)-binding protein 1

2

4

High-throughput

0.631

High

217436

E41L2
Band 4.1-like protein 2

2

4

High-throughput

0.628

High

871925

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

2

1

High-throughput

0.628

High

889724

CLK3
Dual specificity protein kinase CLK3

2

6

High-throughput

0.628

High

1013132

SARNP
SAP domain-containing ribonucleoprotein

2

1

High-throughput

0.628

High

1104946

CUL3
Cullin-3

2

6

High-throughput

0.628

High

1104962

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

2

1

High-throughput

0.628

High

1104968

NKAP
NF-kappa-B-activating protein

2

1

High-throughput

0.625

High

342854

HERC2
E3 ubiquitin-protein ligase HERC2

1

5

High-throughput

0.618

High

472706

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

6

High-throughput

0.618

High

1104957

SMN
Survival motor neuron protein

2

0

High-throughput

0.613

High

134718

SAP18
Histone deacetylase complex subunit SAP18

2

1

High-throughput

0.611

High

1105005

TR150
Thyroid hormone receptor-associated protein 3

2

5

High-throughput

0.611

High

1104992

LUC7L
Putative RNA-binding protein Luc7-like 1

3

3

High-throughput

0.609

High

898634

RL14
Large ribosomal subunit protein eL14

2

0

High-throughput

0.602

High

966275

1433G
14-3-3 protein gamma

2

12

High-throughput

0.601

High

1006377

SRPK2
SRSF protein kinase 2

2

11

High-throughput

0.601

High

977980

RHOB
Rho-related GTP-binding protein RhoB

1

13

Small-scale

0.590

High

1104952

ZMY11
Zinc finger MYND domain-containing protein 11

2

5

Small-scale

0.584

High

1104964

NKAP1
Uncharacterized protein NKAPD1

2

1

High-throughput

0.574

High

286365

DAB1
Disabled homolog 1

1

3

High-throughput

0.573

High

609671

LEG3
Galectin-3

1

3

High-throughput

0.573

High

1086202

TFCP2
Alpha-globin transcription factor CP2

1

1

High-throughput

0.573

High

1104974

KCTD6
BTB/POZ domain-containing protein KCTD6

1

5

High-throughput

0.573

High

464946

SP1
Transcription factor Sp1

1

2

High-throughput

0.561

High

1104975

CEP70
Centrosomal protein of 70 kDa

1

0

High-throughput

0.549

High

1104982

COAC
Phosphopantothenoylcysteine decarboxylase

1

0

High-throughput

0.549

High

1104996

THAP1
THAP domain-containing protein 1

1

0

High-throughput

0.549

High

1105000

DACH1
Dachshund homolog 1

1

0

High-throughput

0.549

High

191633

MAGB2
Melanoma-associated antigen B2

1

3

High-throughput

0.536

High

272924

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

1

High-throughput

0.536

High

574251

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

3

High-throughput

0.536

High

973905

RUXF
Small nuclear ribonucleoprotein F

1

6

High-throughput

0.536

High

1104954

MARE1
Microtubule-associated protein RP/EB family member 1

1

3

High-throughput

0.536

High

1104958

RN151
RING finger protein 151

1

11

High-throughput

0.536

High

1104979

LAR4B
La-related protein 4B

1

5

High-throughput

0.536

High

1104985

SRPK1
SRSF protein kinase 1

1

10

High-throughput

0.536

High

1104988

NUF2
Kinetochore protein Nuf2

1

3

High-throughput

0.536

High

1104991

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

3

High-throughput

0.536

High

1105003

TPX2
Targeting protein for Xklp2

1

1

High-throughput

0.536

High

1105004

E41L3
Band 4.1-like protein 3

1

4

High-throughput

0.536

High

1104961

Q6NVH9
Galectin

1

3

High-throughput

0.515

High

948524

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

973426

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.513

High

994517

YBOX1
Y-box-binding protein 1

1

0

High-throughput

0.513

High

1104998

IKBL1
NF-kappa-B inhibitor-like protein 1

1

0

High-throughput

0.513

High

139703

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

4

High-throughput

0.508

High

280602

PR40A
Pre-mRNA-processing factor 40 homolog A

1

7

High-throughput

0.508

High

889415

CLK1
Dual specificity protein kinase CLK1

1

6

High-throughput

0.501

High

1104978

JPH3
Junctophilin-3

1

1

High-throughput

0.489

High

1105002

ANR50
Ankyrin repeat domain-containing protein 50

1

5

High-throughput

0.489

High

335451

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.486

High

1104972

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.486

High

1104947

FHL3
Four and a half LIM domains protein 3

1

5

High-throughput

0.481

High

1104987

TRI54
Tripartite motif-containing protein 54

1

13

High-throughput

0.481

High

247880

NUPR1
Nuclear protein 1

1

2

High-throughput

0.479

High

259901

BRD4
Bromodomain-containing protein 4

1

6

High-throughput

0.479

High

302507

RNF8
E3 ubiquitin-protein ligase RNF8

1

4

Small-scale

0.479

High

370655

FOS
Protein c-Fos

1

5

High-throughput

0.479

High

371950

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.479

High

400779

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

6

High-throughput

0.479

High

406143

MYCN
N-myc proto-oncogene protein

1

7

High-throughput

0.479

High

459574

PROF1
Profilin-1

1

1

High-throughput

0.479

High

712197

TKT
Transketolase

1

3

High-throughput

0.479

High

761992

GRK5
G protein-coupled receptor kinase 5

1

1

High-throughput

0.479

High

830683

CCNF
Cyclin-F

1

6

High-throughput

0.479

High

879054

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

4

High-throughput

0.479

High

904675

MECP2
Methyl-CpG-binding protein 2

1

7

High-throughput

0.479

High

970450

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

979606

H4
Histone H4

1

3

High-throughput

0.479

High

1035593

KIF23
Kinesin-like protein KIF23

1

5

High-throughput

0.479

High

1045248

TF65
Transcription factor p65

1

2

High-throughput

0.479

High

1085537

FOXO1
Forkhead box protein O1

1

4

High-throughput

0.479

High

1104950

EEA1
Early endosome antigen 1

1

6

High-throughput

0.479

High

1104963

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.479

High

1104965

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

5

High-throughput

0.479

High

1104967

ARMC8
Armadillo repeat-containing protein 8

1

2

High-throughput

0.479

High

1104969

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

4

High-throughput

0.479

High

1104971

ZBT38
Zinc finger and BTB domain-containing protein 38

1

2

Small-scale

0.479

High

1104980

ESR2
Estrogen receptor beta

1

10

High-throughput

0.479

High

1104983

CHM4C
Charged multivesicular body protein 4c

1

3

High-throughput

0.479

High

1104986

DDX23
Probable ATP-dependent RNA helicase DDX23

1

4

High-throughput

0.479

High

1104989

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

2

High-throughput

0.479

High

1104993

ANLN
Anillin

1

3

High-throughput

0.479

High

1104994

RAD18
E3 ubiquitin-protein ligase RAD18

1

1

High-throughput

0.479

High

1104999

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

1104981

Q96C98
FHL3 protein

1

7

High-throughput

0.470

High

1104977

ZCH10
Zinc finger CCHC domain-containing protein 10

1

1

High-throughput

0.464

High

426491

HMGN2
Non-histone chromosomal protein HMG-17

1

0

High-throughput

0.458

High

851550

GATA4
Transcription factor GATA-4

1

0

High-throughput

0.458

High

948420

ARPC4
Actin-related protein 2/3 complex subunit 4

1

0

High-throughput

0.458

High

991837

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.458

High

1104949

NBR1
Next to BRCA1 gene 1 protein

1

0

Small-scale

0.458

High

1104973

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

485622

RU2A
U2 small nuclear ribonucleoprotein A'

1

6

High-throughput

0.445

High

1104959

NCBP3
Nuclear cap-binding protein subunit 3

1

1

High-throughput

0.445

High

1104960

ODFP2
Outer dense fiber protein 2

1

3

High-throughput

0.445

High

1105006

LC7L2
Putative RNA-binding protein Luc7-like 2

1

3

High-throughput

0.445

High

48947

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.426

High

640590

MK
Midkine

2

0

High-throughput

0.328

High

1104970

BEND7
BEN domain-containing protein 7

1

0

High-throughput

0.299

High

1105001

PNMA2
Paraneoplastic antigen Ma2

1

0

High-throughput

0.299

High

488051

IFI6
Interferon alpha-inducible protein 6

1

0

High-throughput

0.279

Low

1092752

MALL
MAL-like protein

1

0

High-throughput

0.279

Low

1104995

TM14B
Transmembrane protein 14B

1

0

High-throughput

0.279

Low

1104997

PEN2
Gamma-secretase subunit PEN-2

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025