HitPredict

Interactor 1: Q53Z40 (Q53Z40)
HCG1 protein (Zinc finger protein 165)
Gene: ZNF165

Interactor 2: ZN446 (Q9NWS9)
Zinc finger protein 446 (Zinc finger protein with KRAB and SCAN domains 20)
Gene: ZNF446

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SCAN~SCAN, zf-C2H2~zf-C2H2
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 485 Hs			1 450
+	Hs
		836579 ZN165_HUMAN (1-481): 1.16e-169: 488: 100.00		ZN165_HUMAN (15-448): 6.3e-115: 347: 24.29
+	Hs
		836614 ZN165_HUMAN (1-481): 1.16e-169: 488: 100.00		ZN446_HUMAN (1-450): 1.58e-114: 345: 100.00
+	Hs
		1281562 ZKSC4_HUMAN (1-482): 2.21e-148: 436: 36.83		ZKSC4_HUMAN (11-449): 8.19e-125: 375: 23.51
+	Hs
		836589 ZN165_HUMAN (1-481): 1.16e-169: 488: 100.00		ZKSC8_HUMAN (188-421): 1.29e-86: 277: 16.92
+	Hs
		161799 ZN165_HUMAN (1-481): 1.16e-169: 488: 100.00		ZN263_HUMAN (123-450): 3.51e-68: 231: 17.88
+	Hs
		1078412 ZKSC4_HUMAN (1-482): 2.21e-148: 436: 36.83		ZKSC8_HUMAN (188-421): 1.29e-86: 277: 16.92
+	Hs
		1257092 ZKSC4_HUMAN (1-482): 2.21e-148: 436: 36.83		ZN483_HUMAN (231-449): 1.69e-74: 249: 23.55
+	Hs
		563726 ZKSC4_HUMAN (1-482): 2.21e-148: 436: 36.83		ZKSC1_HUMAN (95-421): 2.39e-74: 244: 14.29
+	Hs
		549144 ZN165_HUMAN (1-481): 1.16e-169: 488: 100.00		ZN250_HUMAN (17-299): 1.24e-50: 182: 8.14
+	Hs
		1109820 ZKSC4_HUMAN (1-482): 2.21e-148: 436: 36.83		ZSC23_HUMAN (329-450): 5.69e-47: 168: 29.51
+	Hs
		1202827 ZKSC4_HUMAN (1-482): 2.21e-148: 436: 36.83		ZSC30_HUMAN (340-450): 5.51e-37: 143: 28.83
+	Hs
		154563 ZKSC4_HUMAN (1-482): 2.21e-148: 436: 36.83		ZN213_HUMAN (369-450): 9.71e-34: 133: 32.18
+	Hs
		1281570 ZKSC4_HUMAN (1-482): 2.21e-148: 436: 36.83		ZKSC3_HUMAN (142-329): 7.96e-30: 123: 6.79
+	Hs
		1163707 ZKSC4_HUMAN (1-482): 2.21e-148: 436: 36.83		SCND3_HUMAN (23-152): 1.74e-27: 118: 48.15
+	Hs
		1281565 ZKSC4_HUMAN (1-482): 2.21e-148: 436: 36.83		ZN496_HUMAN (15-445): 5.55e-28: 118: 30.57
+	Hs
		1281566 ZKSC4_HUMAN (1-482): 2.21e-148: 436: 36.83		PGBD1_HUMAN (23-209): 3.3e-23: 104: 36.90
+	Hs
		3502 ZKSC4_HUMAN (1-482): 2.21e-148: 436: 36.83		A0A0S2Z6X0_HUMAN (12-105): 1.81e-25: 103: 62.77
+	Hs
		1244154 ZKSC4_HUMAN (1-482): 2.21e-148: 436: 36.83		ZN397_HUMAN (392-449): 6.34e-21: 97.4: 41.38
+	Hs
		485187 ZKSC4_HUMAN (1-482): 2.21e-148: 436: 36.83		ZSC22_HUMAN (52-167): 2.23e-13: 73.9: 8.55
+	Hs
		563837 ZKSC4_HUMAN (1-482): 2.21e-148: 436: 36.83		ZSC20_HUMAN (330-445): 2.1e-09: 62: 33.06