HitPredict

Interactor 1: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Interactor 2: LUZP1 (Q86V48)
Leucine zipper protein 1 (Filamin mechanobinding actin cross-linking protein) (Fimbacin)
Gene: LUZP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26638075, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005874 - microtubule GO:0008017 - microtubule binding GO:0016020 - membrane and 1 others more... GO:0036064 - ciliary basal body
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1278 Hs			1 1076
+	Hs
		1106264 DCTN1_HUMAN (1-1278): 7.7e-92: 325: 100.00		ROCK1_HUMAN (83-619): 3.75e-26: 118: 12.09
+	Hs
		157361 DCTN1_HUMAN (1-1278): 7.7e-92: 325: 100.00		CTRO_HUMAN (27-558): 1.53e-24: 113: 12.04
+	Hs
		1123651 DCTN1_HUMAN (1-1278): 7.7e-92: 325: 100.00		GRDN_HUMAN (10-513): 1.42e-09: 64.9: 17.82
+	Mm
		1037835 MYH1_MOUSE (402-1277): 1.06e-36: 153: 10.75		MYH6_MOUSE (3-524): 7.14e-21: 101: 9.59
+	Hs
		563056 MYH8_HUMAN (402-1273): 1.58e-35: 149: 9.99		EEA1_HUMAN (1-532): 6.87e-22: 104: 10.40
+	Hs
		563081 MYH8_HUMAN (402-1273): 1.58e-35: 149: 9.99		MYH4_HUMAN (3-525): 2.84e-20: 99.8: 10.11
+	Hs
		563078 MYH13_HUMAN (382-1278): 1.77e-38: 159: 9.99		MYH8_HUMAN (1-296): 8.49e-11: 68.6: 13.42
+	Mm
		1037830 MYH6_MOUSE (47-740): 5.08e-26: 119: 10.09		MYH6_MOUSE (3-524): 7.14e-21: 101: 9.59
+	Hs
		773038 KI13B_HUMAN (14-145): 5.01e-32: 138: 32.85		MYH9_HUMAN (1-353): 3.2e-12: 73.3: 13.65
+	Hs
		721004 CLIP1_HUMAN (111-828): 1.38e-21: 104: 11.32		EEA1_HUMAN (1-532): 6.87e-22: 104: 10.40
+	Hs
		556973 MYH7_HUMAN (62-738): 7.85e-23: 108: 9.87		MYH4_HUMAN (3-525): 2.84e-20: 99.8: 10.11
+	Hs
		1154188 CLIP2_HUMAN (26-552): 7.5e-22: 104: 17.63		ITSN1_HUMAN (106-476): 2.88e-18: 93.3: 9.61
+	Hs
		562992 MYH6_HUMAN (47-740): 4.47e-26: 119: 10.38		MYH6_HUMAN (333-813): 1.19e-10: 68.2: 7.80
+	Mm
		563088 MYH6_MOUSE (47-740): 5.08e-26: 119: 10.09		MYH8_MOUSE (2-263): 1.41e-09: 64.8: 13.28
+	Hs
		556902 MYH7_HUMAN (62-738): 7.85e-23: 108: 9.87		MYH9_HUMAN (1-353): 3.2e-12: 73.3: 13.65
+	Hs
		535921 MYH6_HUMAN (47-740): 4.47e-26: 119: 10.38		MYH3_HUMAN (6-254): 8.2e-09: 62.2: 15.44
+	Hs
		535945 CLIP4_HUMAN (6-95): 3.81e-26: 118: 42.22		MYH3_HUMAN (6-254): 8.2e-09: 62.2: 15.44
+	Hs
		556892 MYH7_HUMAN (62-738): 7.85e-23: 108: 9.87		MYH7_HUMAN (5-340): 3.18e-10: 66.7: 13.49