HitPredict

Interactor 1: IQEC2 (Q5DU25)
IQ motif and SEC7 domain-containing protein 2
Gene: Iqsec2

Interactor 2: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.706

Property	Details
Experiments	27507650, 28671696, 36417873, 36604605, 19455133
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0051965 - positive regulation of synapse assembly GO:0098839 - postsynaptic density membrane GO:0098978 - glutamatergic synapse
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1478 Mm			1 724
+	Hs
		1021511 IQEC2_HUMAN (1-1478): 0: 1161: 97.38		DLG1_HUMAN (28-724): 0: 576: 72.79
+	Mm
		1143447 IQEC1_MOUSE (220-1157): 0: 774: 58.87		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Hs
		1021514 IQEC1_HUMAN (220-1167): 0: 755: 57.95		DLG1_HUMAN (28-724): 0: 576: 72.79
+	Mm
		926281 CYH2_MOUSE (686-1076): 5.45e-122: 388: 23.35		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Mm
		140105 CYH3_MOUSE (708-1076): 1.56e-120: 384: 24.73		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Hs
		1255112 GBF1_HUMAN (657-942): 1.47e-84: 308: 29.93		DLG5_HUMAN (40-245): 4.01e-17: 88.6: 31.55