HitPredict

Interactor 1: EXOS6 (Q5RKV6)
Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog) (hMtr3) (p11)
Gene: EXOSC6

Interactor 2: MPH6 (Q99547)
M-phase phosphoprotein 6
Gene: MPHOSPH6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	24981860, 28877463, 33961781
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000178 - exosome (RNase complex) GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus and 1 others more... GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 272 Hs			1 160
+	Hs
		1304448 EXOS4_HUMAN (20-267): 1.16e-77: 237: 26.51		MPH6_HUMAN (1-160): 1.95e-67: 203: 100.00
+	Hs
		110631 EXOS4_HUMAN (20-267): 1.16e-77: 237: 26.51		H3BNT4_HUMAN (19-160): 1.34e-58: 180: 100.00
+	Hs
		1284955 EXOS8_HUMAN (16-265): 1.31e-63: 202: 16.19		MPH6_HUMAN (1-160): 1.95e-67: 203: 100.00
+	Hs
		1063758 EXOS7_HUMAN (11-271): 3.95e-56: 183: 17.07		MPH6_HUMAN (1-160): 1.95e-67: 203: 100.00
+	Hs
		986713 EXOS9_HUMAN (9-271): 3.87e-49: 169: 13.22		MPH6_HUMAN (1-160): 1.95e-67: 203: 100.00
+	Hs
		1304449 EXOS5_HUMAN (12-266): 2.68e-49: 164: 25.29		MPH6_HUMAN (1-160): 1.95e-67: 203: 100.00
+	Hs
		110628 EXOS9_HUMAN (9-271): 3.87e-49: 169: 13.22		H3BNT4_HUMAN (19-160): 1.34e-58: 180: 100.00
+	Hs
		110632 EXOS5_HUMAN (12-266): 2.68e-49: 164: 25.29		H3BNT4_HUMAN (19-160): 1.34e-58: 180: 100.00