HitPredict

Interactor 1: NCOA6 (Q14686)
Nuclear receptor coactivator 6 (Activating signal cointegrator 2) (ASC-2) (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Nuclear receptor-activating protein, 250 kDa) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Thyroid hormone receptor-binding protein)
Gene: NCOA6

Interactor 2: TNR6A (Q8NDV7)
Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa)
Gene: TNRC6A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28813667
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2063 Hs			1 1962
+	Hs
		1129656 MDC1_HUMAN (200-1117): 1.49e-18: 95.4: 12.08		TNR6A_HUMAN (1-1962): 0: 894: 100.00
+	Hs
		154721 ARI1A_HUMAN (513-2060): 1.17e-10: 69.4: 9.40		TNR6A_HUMAN (1-1962): 0: 894: 100.00
+	Hs
		1067333 NCOA6_HUMAN (1-2063): 0: 739: 100.00		EP300_HUMAN (740-1745): 3.78e-36: 153: 10.61
+	Hs
		1130587 NCOA6_HUMAN (1-2063): 0: 739: 100.00		CBP_HUMAN (735-1745): 9.49e-21: 102: 9.54
+	Mm
		1297309 NCOA6_MOUSE (1-2063): 0: 720: 90.77		KMT2C_MOUSE (670-1797): 5.03e-24: 113: 8.80
+	Hs
		1130579 NCOA6_HUMAN (1-2063): 0: 739: 100.00		KMT2C_HUMAN (1065-1769): 3.93e-12: 74.5: 13.16
+	Hs
		590279 MUC1_HUMAN (93-924): 1.57e-36: 154: 8.76		EP300_HUMAN (740-1745): 3.78e-36: 153: 10.61
+	Hs
		1403962 MUC4_HUMAN (1118-2062): 2.05e-21: 105: 10.27		MUC4_HUMAN (48-1798): 3.92e-47: 189: 9.66
+	Dm
		1481145 Q9VLS7_DROME (1107-2063): 3.4e-18: 94.1: 9.40		Q9VXR3_DROME (1321-1891): 7.89e-41: 169: 13.36
+	Hs
		1067330 MDC1_HUMAN (200-1117): 1.49e-18: 95.4: 12.08		EP300_HUMAN (740-1745): 3.78e-36: 153: 10.61
+	Hs
		1067605 ZN469_HUMAN (807-2063): 4.35e-17: 90.6: 9.77		EP300_HUMAN (740-1745): 3.78e-36: 153: 10.61
+	Hs
		590235 MUC1_HUMAN (93-924): 1.57e-36: 154: 8.76		MUC1_HUMAN (845-1740): 2.02e-15: 84.9: 11.69
+	Hs
		334291 TACC2_HUMAN (667-2031): 1.82e-15: 85.2: 9.89		EP300_HUMAN (740-1745): 3.78e-36: 153: 10.61
+	Hs
		1067841 BSN_HUMAN (170-1978): 3.29e-13: 77.9: 8.12		EP300_HUMAN (740-1745): 3.78e-36: 153: 10.61
+	Mm
		59396 ARI1A_MOUSE (517-2060): 1.54e-15: 85.6: 8.74		CHD7_MOUSE (985-1540): 9.07e-32: 139: 12.15
+	Hs
		1129671 MDC1_HUMAN (200-1117): 1.49e-18: 95.4: 12.08		CBP_HUMAN (735-1745): 9.49e-21: 102: 9.54
+	Hs
		1431709 TARA_HUMAN (990-1818): 2.95e-19: 97.9: 12.34		TARA_HUMAN (728-1792): 9.49e-18: 92.8: 9.86
+	Hs
		334311 TACC2_HUMAN (667-2031): 1.82e-15: 85.2: 9.89		CBP_HUMAN (735-1745): 9.49e-21: 102: 9.54
+	Mm
		1455913 PCLO_MOUSE (142-2041): 7.46e-13: 76.8: 8.36		PCLO_MOUSE (5-1055): 2.95e-14: 81.3: 9.87
+	Hs
		154767 ARI1A_HUMAN (513-2060): 1.17e-10: 69.4: 9.40		CHD7_HUMAN (1220-1764): 8.15e-14: 79.8: 11.71