HitPredict

Interactor 1: TPC3L (Q5T215)
Trafficking protein particle complex subunit 3-like protein (TRAPPC3-like protein) (BET3-like protein)
Gene: TRAPPC3L

Interactor 2: TPC2L (Q9UL33)
Trafficking protein particle complex subunit 2-like protein
Gene: TRAPPC2L

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	21525244
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Sedlin_N~TRAPP
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005829 - cytosol GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0030008 - TRAPP complex
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 181 Hs			1 140
+	Hs
		208753 TPPC3_HUMAN (1-181): 2.98e-105: 301: 61.88		TPC2L_HUMAN (1-140): 7.52e-64: 193: 100.00
+	Hs
		208704 TPPC3_HUMAN (1-181): 2.98e-105: 301: 61.88		TPC2A_HUMAN (2-135): 2.72e-41: 136: 21.83
+	Hs
		208705 TPPC3_HUMAN (1-181): 2.98e-105: 301: 61.88		TPC2B_HUMAN (2-135): 2.72e-41: 136: 21.83
+	Mm
		222946 TPPC3_MOUSE (1-181): 5.69e-105: 300: 61.33		TPPC2_MOUSE (2-135): 4.54e-42: 137: 21.83
+	Hs
		483311 TPC3L_HUMAN (1-181): 8.84e-103: 294: 100.00		TPC2B_HUMAN (2-135): 2.72e-41: 136: 21.83
+	Dm
		53204 Q9VSY8_DROME (1-181): 1.29e-89: 261: 46.41		A1Z8I0_DROME (1-136): 3.36e-53: 166: 54.41
+	Dm
		87961 Q9VSY8_DROME (1-181): 1.29e-89: 261: 46.41		D3DMJ4_DROME (1-136): 4.04e-53: 166: 54.41
+	Sc
		733728 BET3_YEAST (10-181): 1.3e-86: 254: 46.82		TRS20_YEAST (1-135): 2.5e-41: 137: 26.04
+	Dm
		1373754 Q9VSY8_DROME (1-181): 1.29e-89: 261: 46.41		TPPC2_DROME (2-131): 1.8e-32: 113: 19.86
+	Ce
		137381 TPPC3_CAEEL (8-181): 7.86e-68: 206: 39.55		TPPC2_CAEEL (3-133): 4.64e-38: 127: 24.29